Completed PHASE3 INTERVENTIONAL NCT00003701

Combination Chemotherapy in Treating Patients With Bladder Cancer

A Phase III Randomized Trial of Either M-VAC or Paclitaxel + Carboplatin as Postoperative Adjuvant Therapy in Patients With Muscle-Invasive Transitional Cell Carcinoma of the Bladder at High-Risk for Relapse

Sponsor: Eastern Cooperative Oncology Group

Conditions Bladder Cancer Urethral Cancer

Interventions carboplatin cisplatin doxorubicin hydrochloride methotrexate paclitaxel vinblastine sulfate

Updated 7 times since 2017 Last updated: Jun 13, 2023 Started: Apr 2, 1999 Primary completion: Aug 31, 2001 Completion: Jun 15, 2007

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00003701, this PHASE3 trial focuses on Bladder Cancer and Urethral Cancer and remains completed. Sponsored by Eastern Cooperative Oncology Group, it has been updated 7 times since 1999, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

Change History

7 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jul 2023 — Jul 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2023 [monthly]

Completed PHASE3
Feb 2019 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 2 earlier versions

Jun 2018 — Feb 2019 [monthly]

Completed PHASE3
Jan 2017 — Jun 2018 [monthly]

Completed PHASE3

First recorded

Apr 1999

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Data source: Eastern Cooperative Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Cleveland, United States , Decatur, United States , Flemington, United States , Hackensack, United States , Indianapolis, United States , Millville, United States , Mount Holly, United States , Nashville, United States , New York, United States , Philadelphia, United States and 2 more locations