deltatrials
Completed PHASE3 NCT00003994

Combination Chemotherapy With or Without Amifostine in Treating Young Patients With Liver Cancer

Intergroup Protocol for Treatment of Children With Hepatoblastoma

Sponsor: Children's Oncology Group

Conditions Childhood Hepatoblastoma Recurrent Childhood Liver Cancer Stage I Childhood Liver Cancer
Interventions amifostine trihydrate carboplatin cisplatin fluorouracil therapeutic conventional surgery vincristine sulfate
Updated 6 times since 2017 Last updated: Jun 13, 2013 Started: Mar 31, 1999 Primary completion: Oct 31, 2007

A PHASE3 clinical study on Childhood Hepatoblastoma and Recurrent Childhood Liver Cancer, this trial is completed. The trial is conducted by Children's Oncology Group and has accumulated 6 data snapshots since 1999. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Change History

6 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  4. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE3

  5. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE3

▶ Show 1 earlier version

  1. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE3

    First recorded

Mar 1999

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Children's Oncology Group
  • National Cancer Institute (NCI)
Data source: Children's Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

  • • Arcadia, United States