deltatrials
Completed PHASE3 NCT00004218

Chemotherapy in Treating Patients With Newly Diagnosed Chronic Lymphocytic Leukemia

Chronic Lymphocytic Leukemia Trial 4: A Randomized Comparison of Chlorambucil, Fludarabine and Fludarabine Plus Cyclophosphamide

Sponsor: Leukemia Research Fund

Conditions Leukemia
Interventions chlorambucil cyclophosphamide doxorubicin hydrochloride fludarabine phosphate prednisolone vincristine sulfate
Updated 6 times since 2017 Last updated: Dec 17, 2013 Started: Oct 31, 1999 Completion: Jul 31, 2007

This PHASE3 trial investigates Leukemia and is currently completed. Leukemia Research Fund leads this study, which shows 6 recorded versions since 1999 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Change History

6 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE3

▶ Show 1 earlier version

  1. Jan 2017 — Jun 2018 [monthly]

    Completed PHASE3

    First recorded

Oct 1999

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Leukemia Research Fund
  • Medical Research Council
Data source: National Cancer Institute (NCI)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aberdeen, United Kingdom, Airdrie, United Kingdom, Aylesbury-Buckinghamshire, United Kingdom, Banbury, United Kingdom, Bangor, United Kingdom, Basingstoke, United Kingdom, Belfast, United Kingdom, Bergamo, Italy, Birmingham, United Kingdom, Blackpool, United Kingdom and 67 more location s