Completed NA INTERVENTIONAL NCT00005013

Treatment of Major Depression With St. John's Wort (Hypericum)

A Placebo Controlled Clinical Trial of a Standardized Extract of Hypericum Perforatum in Major Depressive Disorder

Sponsor: National Center for Complementary and Integrative Health (NCCIH)

Interventions Hypericum perforatum (St. John's wort) Sertraline

Updated 5 times since 2017 Last updated: Apr 7, 2014 Started: Dec 31, 1998 Completion: Jul 31, 2001

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Major Depression and is currently completed. National Center for Complementary and Integrative Health (NCCIH) leads this study, which shows 5 recorded versions since 1998 — indicating limited longitudinal coverage. This study adds to the longitudinal dataset for psychiatric treatment development.

Status Flow

Change History

5 versions recorded

Sep 2024 — Present [monthly]

Completed NA
Jul 2024 — Sep 2024 [monthly]

Completed NA
Jan 2021 — Jul 2024 [monthly]

Completed NA
Jun 2018 — Jan 2021 [monthly]

Completed NA
Jan 2017 — Jun 2018 [monthly]

Completed NA

First recorded

Dec 1998

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

National Center for Complementary and Integrative Health (NCCIH)
National Institute of Mental Health (NIMH)

Data source: National Institute of Mental Health (NIMH)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Atlanta, United States , Belmont, United States , Cincinnati, United States , Dallas, United States , Durham, United States , Middleton, United States , New York, United States , San Diego, United States , Seattle, United States , Stanford, United States and 2 more locations