Completed PHASE3 INTERVENTIONAL 2-arm NCT00009620

Antenatal Phenobarbital to Prevent Neonatal Intracranial Hemorrhage (Phenobarbital)

Randomized Clinical Trial of Antenatal Phenobarbital in the Prevention of Neonatal Intracranial Hemorrhage

Sponsor: NICHD Neonatal Research Network

Conditions Infant, Low Birth Weight Infant, Newborn Infant, Premature Infant, Small for Gestational Age Intracranial Hemorrhages

Interventions Phenobarbital Saline

Updated 8 times since 2017 Last updated: Mar 20, 2019 Started: Feb 28, 1993 Primary completion: Feb 28, 1995 Completion: Feb 28, 1997

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00009620, this PHASE3 trial focuses on Infant, Low Birth Weight and Infant, Newborn and remains completed. Sponsored by NICHD Neonatal Research Network, it has been updated 8 times since 1993, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Apr 2019 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 3 earlier versions

Jun 2018 — Apr 2019 [monthly]

Completed PHASE3
Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Feb 1993

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

NICHD Neonatal Research Network
National Center for Research Resources (NCRR)

Data source: NICHD Neonatal Research Network

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albuquerque, United States , Atlanta, United States , Cincinnati, United States , Cleveland, United States , Detroit, United States , Indianapolis, United States , Memphis, United States , New Haven, United States , Palo Alto, United States , Providence, United States and 1 more location