Completed PHASE3 INTERVENTIONAL NCT00025090

Radiation Therapy Plus Fluorouracil With or Without Additional Chemotherapy in Treating Patients With Primary Anal Cancer

Second UK Phase III Anal Cancer Trial: A Trial of Chemoradiation and Maintenance Therapy for Patients With Anal Cancer

Sponsor: University College London (UCL) Cancer Institute

Interventions cisplatin fluorouracil mitomycin C radiation therapy

Updated 6 times since 2017 Last updated: Aug 23, 2013 Started: Mar 31, 2001 Completion: Aug 31, 2007

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Anal Cancer, this trial is completed. The trial is conducted by University College London (UCL) Cancer Institute and has accumulated 6 data snapshots since 2001. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

Change History

6 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 1 earlier version

Jan 2017 — Jun 2018 [monthly]

Completed PHASE3

First recorded

Mar 2001

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

University College London (UCL) Cancer Institute

Data source: National Cancer Institute (NCI)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aberdeen, United Kingdom , Cardiff, United Kingdom , Harrow, United Kingdom , Ipswich, United Kingdom , Leeds, United Kingdom , London, United Kingdom , Middlesbrough, United Kingdom , Northwood, United Kingdom , Nottingham, United Kingdom , Sheffield, United Kingdom and 2 more locations