Unknown PHASE3 INTERVENTIONAL NCT00025402

Chemotherapy and Biological Therapy With or Without Bone Marrow or Peripheral Stem Cell Transplant in Treating Patients With Chronic Myelogenous Leukemia

Randomized Multicenter Treatment Optimization Study In Chronic Myeloid Leukemia (CML) Interferon-a Vs. Allogeneic Stem Cell Transplantation Vs. High-Dose Chemotherapy Followed By Autografting And Interferon-a Maintainance In Early Chronic Phase

Sponsor: III. Medizinische Klinik Mannheim

Conditions Leukemia

Interventions allogeneic bone marrow transplantation busulfan cyclophosphamide cytarabine etoposide filgrastim hydroxyurea idarubicin peripheral blood stem cell transplantation radiation therapy recombinant interferon alfa

Updated 6 times since 2017 Last updated: Dec 17, 2013 Started: Jul 31, 1997

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Leukemia, this trial is ongoing. The trial is conducted by III. Medizinische Klinik Mannheim and has accumulated 6 data snapshots since 1997. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

Change History

6 versions recorded

Sep 2025 — Present [monthly]

Unknown PHASE3
Sep 2024 — Sep 2025 [monthly]

Unknown PHASE3
Jul 2024 — Sep 2024 [monthly]

Unknown PHASE3

Status: Unknown Status → Unknown
Jan 2021 — Jul 2024 [monthly]

Unknown Status PHASE3
Jun 2018 — Jan 2021 [monthly]

Unknown Status PHASE3

▶ Show 1 earlier version

Jan 2017 — Jun 2018 [monthly]

Unknown Status PHASE3

First recorded

Jul 1997

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

III. Medizinische Klinik Mannheim

Data source: National Cancer Institute (NCI)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aachen, Germany , Aalen, Germany , Aarau, Switzerland , Amberg, Germany , Ansbach, Germany , Aschaffenburg, Germany , Augsburg, Germany , Baar, Switzerland , Bad Hersfeld, Germany , Basel, Switzerland and 113 more locations