Completed PHASE3 INTERVENTIONAL 6-arm NCT00049517

Combination Chemotherapy With or Without Monoclonal Antibody Therapy in Treating Patients With AML Leukemia

A Phase III Trial in Adult Acute Myeloid Leukemia: Daunorubicin Dose-Intensification Prior to Risk-Allocated Autologous Stem Cell Transplantation

Sponsor: Eastern Cooperative Oncology Group

Conditions Leukemia

Interventions Allogeneic HCT Autologous HCT Daunorubicin busulfan cyclophosphamide cytarabine gemtuzumab ozogamicin (GO) sargramostim

Updated 11 times since 2017 Last updated: Jun 13, 2023 Started: Dec 19, 2002 Primary completion: Mar 31, 2009 Completion: Dec 31, 2019

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00049517, this PHASE3 trial focuses on Leukemia and remains completed. Sponsored by Eastern Cooperative Oncology Group, it has been updated 11 times since 2002, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

Change History

11 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jul 2023 — Jul 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2023 [monthly]

Completed PHASE3

▶ Show 6 earlier versions

Dec 2020 — Jan 2021 [monthly]

Completed PHASE3

Status: Active Not Recruiting → Completed
Oct 2019 — Dec 2020 [monthly]

Active Not Recruiting PHASE3
Feb 2019 — Oct 2019 [monthly]

Active Not Recruiting PHASE3
Jun 2018 — Feb 2019 [monthly]

Active Not Recruiting PHASE3
Feb 2017 — Jun 2018 [monthly]

Active Not Recruiting PHASE3
Jan 2017 — Feb 2017 [monthly]

Active Not Recruiting PHASE3

First recorded

Dec 2002

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Eastern Cooperative Oncology Group
National Cancer Institute (NCI)

Data source: Eastern Cooperative Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Atlanta, United States , Aurora, United States , Bemidji, United States , Billings, United States , Birmingham, United States , Boca Raton, United States , Boston, United States , Bozeman, United States , Burnsville, United States , Butte, United States and 63 more locations