Completed PHASE3 INTERVENTIONAL NCT00051272

Effects Of Antidepressants On Sexual Functioning In Adults

A Multicenter, Double-blind Randomized Placebo-controlled Comparison of the Effects on Sexual Functioning of Extended-release Bupropion Hydrochloride (300-450mg) and Escitalopram (10-20mg) in Outpatients With Moderate to Severe Major Depression Over an Eight-Week Treatment Period

Sponsor: GlaxoSmithKline

Conditions Major Depressive Disorder (MDD)

Interventions Extended-release Bupropion Hydrochloride

Updated 7 times since 2017 Last updated: Mar 28, 2011 Started: Jan 31, 2003 Primary completion: Jun 30, 2004 Completion: Jun 30, 2004

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00051272, this PHASE3 trial focuses on Major Depressive Disorder (MDD) and remains completed. Sponsored by GlaxoSmithKline, it has been updated 7 times since 2003, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

7 versions recorded

Jan 2026 — Present [monthly]

Completed PHASE3
Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3

▶ Show 2 earlier versions

Jun 2018 — Jan 2021 [monthly]

Completed PHASE3
Jan 2017 — Jun 2018 [monthly]

Completed PHASE3

First recorded

Jan 2003

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

GlaxoSmithKline

Data source: GlaxoSmithKline

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Baton Rouge, United States , Bellaire, United States , Berkeley, United States , Boise, United States , Braintree, United States , Cleveland, United States , Marietta, United States , Middletown, United States , Nashville, United States , New York, United States and 12 more locations