deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT00059930

Adjuvant Hepatic Arterial Infusion and Combination Chemotherapy in Treating Patients With Resectable Hepatic Metastases From Colorectal Cancer

A Phase I Study Of Hepatic Arterial Infusion With Floxuridine And Dexamethasone In Combination With Intravenous Oxaliplatin Plus 5-Fluorouracil And Leucovorin As Adjuvant Treatment After Resection Of Hepatic Metastases From Colorectal Cancer

Sponsor: Memorial Sloan Kettering Cancer Center

Conditions Colorectal Cancer Metastatic Cancer
Interventions FOLFOX regimen adjuvant therapy conventional surgery dexamethasone floxuridine fluorouracil leucovorin calcium oxaliplatin
Updated 16 times since 2017 Last updated: Mar 25, 2025 Started: Jan 31, 2003 Primary completion: Mar 24, 2025 Completion: Mar 24, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00059930, this PHASE1 trial focuses on Colorectal Cancer and Metastatic Cancer and remains completed. Sponsored by Memorial Sloan Kettering Cancer Center, it has been updated 16 times since 2003, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshot~Aug 2017 – ~Jun 2018 · 10 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Jul 2019 · 12 months · monthly snapshot~Jul 2019 – ~Nov 2019 · 4 months · monthly snapshot~Nov 2019 – ~Oct 2020 · 11 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshot~Sep 2021 – ~Sep 2022 · 12 months · monthly snapshot~Sep 2022 – ~Aug 2023 · 11 months · monthly snapshot~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Apr 2025 · 7 months · monthly snapshot~Apr 2025 – present · 17 months · monthly snapshot

Change History

16 versions recorded

  1. Apr 2025 — Present [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed

  2. Sep 2024 — Apr 2025 [monthly]

    Active Not Recruiting PHASE1

  3. Aug 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

  4. Jul 2024 — Aug 2024 [monthly]

    Active Not Recruiting PHASE1

  5. Aug 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

▶ Show 11 earlier versions

  1. Sep 2022 — Aug 2023 [monthly]

    Active Not Recruiting PHASE1

  2. Sep 2021 — Sep 2022 [monthly]

    Active Not Recruiting PHASE1

  3. Jan 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE1

  4. Oct 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE1

  5. Nov 2019 — Oct 2020 [monthly]

    Active Not Recruiting PHASE1

  6. Jul 2019 — Nov 2019 [monthly]

    Active Not Recruiting PHASE1

  7. Jul 2018 — Jul 2019 [monthly]

    Active Not Recruiting PHASE1

  8. Jun 2018 — Jul 2018 [monthly]

    Active Not Recruiting PHASE1

  9. Aug 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1

  10. Feb 2017 — Aug 2017 [monthly]

    Active Not Recruiting PHASE1

  11. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE1

    First recorded

Jan 2003

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Memorial Sloan Kettering Cancer Center
  • National Cancer Institute (NCI)
  • University of Medicine and Dentistry of New Jersey
Data source: Memorial Sloan Kettering Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations