Study of Lonafarnib Versus Placebo in Subjects With Either Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML) (Study P02978AM3)(TERMINATED)
A Pivotal Randomized Study of Lonafarnib Versus Placebo in the Treatment of Subjects With Myelodysplastic Syndrome (MDS) or Chronic Myelomonocytic Leukemia (CMML) Who Are Platelet Transfusion Dependent With or Without Anemia
Sponsor: Merck Sharp & Dohme LLC
Terminated
This trial was terminated. No reason was provided.
Other terminated trials from Merck Sharp & Dohme LLC
- Melanoma · Phase PHASE2 · Feb 2026
- Advanced Solid Tumor · Phase PHASE2 · Jan 2026
- Lung Cancer Metastatic · Phase PHASE1/PHASE2 · Dec 2025
- Advanced and Metastatic Urothelial Cancer · Phase PHASE2 · Sep 2025
- Malignant Solid Tumor · Phase PHASE1 · Aug 2025
More terminations from Merck Sharp & Dohme LLC
Other Leukemia, Myelomonocytic, Chronic trials with similar outcome
Listed as NCT00109538, this PHASE3 trial focuses on Leukemia, Myelomonocytic, Chronic and Myelodysplasia and remains terminated or withdrawn. Sponsored by Merck Sharp & Dohme LLC, it has been updated 8 times since 2005, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.
Status Flow
Change History
8 versions recorded-
Sep 2024 — Present [monthly]
Terminated PHASE3
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Jul 2024 — Sep 2024 [monthly]
Terminated PHASE3
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Jun 2022 — Jul 2024 [monthly]
Terminated PHASE3
-
Apr 2022 — Jun 2022 [monthly]
Terminated PHASE3
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Jan 2021 — Apr 2022 [monthly]
Terminated PHASE3
▶ Show 3 earlier versions
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Jun 2018 — Jan 2021 [monthly]
Terminated PHASE3
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Feb 2017 — Jun 2018 [monthly]
Terminated PHASE3
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Jan 2017 — Feb 2017 [monthly]
Terminated PHASE3
First recorded
May 2005
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Merck Sharp & Dohme LLC
For direct contact, visit the study record on ClinicalTrials.gov .
Study Locations
No location information available.