deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT00879034

A Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria

A Phase II Pilot Study of Zoledronic Acid, Pravastatin, and Lonafarnib (SCH66336) for Patients With Hutchinson-Gilford Progeria Syndrome (HGPS) and Progeroid Laminopathies

Sponsor: Boston Children's Hospital

Conditions Hutchinson-Gilford Syndrome Progeria
Interventions Lonafarnib Pravastatin Zoledronic Acid
Updated 12 times since 2017 Last updated: Jun 11, 2019 Started: Mar 31, 2009 Primary completion: Apr 30, 2009 Completion: Apr 30, 2009
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Hutchinson-Gilford Syndrome and Progeria, this trial is completed. The trial is conducted by Boston Children's Hospital and has accumulated 12 data snapshots since 2009. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Sep 2017 · 7 months · monthly snapshotCompleted~Sep 2017 – ~Jun 2018 · 9 months · monthly snapshotCompleted~Jun 2018 – ~Jul 2019 · 13 months · monthly snapshotCompleted~Jul 2019 – ~Sep 2020 · 14 months · monthly snapshotCompleted~Sep 2020 – ~Jan 2021 · 4 months · monthly snapshotCompleted~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotCompleted~Dec 2021 – ~Dec 2022 · 12 months · monthly snapshotCompleted~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshotCompleted~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

12 versions recorded

  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE2

  4. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE2

  5. Dec 2021 — Dec 2022 [monthly]

    Completed PHASE2

▶ Show 7 earlier versions

  1. Jan 2021 — Dec 2021 [monthly]

    Completed PHASE2

  2. Sep 2020 — Jan 2021 [monthly]

    Completed PHASE2

  3. Jul 2019 — Sep 2020 [monthly]

    Completed PHASE2

  4. Jun 2018 — Jul 2019 [monthly]

    Completed PHASE2

  5. Sep 2017 — Jun 2018 [monthly]

    Completed PHASE2

  6. Feb 2017 — Sep 2017 [monthly]

    Completed PHASE2

  7. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE2

    First recorded

Mar 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Boston Children's Hospital
  • Brigham and Women's Hospital
  • Dana-Farber Cancer Institute
  • Schering-Plough
Data source: Boston Children's Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations