Completed PHASE3 INTERVENTIONAL 2-arm NCT00262795

Fludarabine or Chlorambucil as First-Line Therapy in Treating Older Patients With Previously Untreated Chronic Lymphocytic Leukemia

Fludarabine Versus Chlorambucil in First Line Therapy of Elderly Patients (More Than 65 Years) With Advanced Chronic Lymphocytic Leukemia

Sponsor: German CLL Study Group

Conditions Chronic Lymphocytic Leukemia

Interventions Chlorambucil Fludarabine

Updated 7 times since 2017 Last updated: May 21, 2019 Started: Sep 30, 2003 Primary completion: Jan 31, 2005 Completion: Oct 31, 2005

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Chronic Lymphocytic Leukemia, this trial is completed. The trial is conducted by German CLL Study Group and has accumulated 7 data snapshots since 2003. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jun 2019 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 2 earlier versions

Jun 2018 — Jun 2019 [monthly]

Completed PHASE3
Jan 2017 — Jun 2018 [monthly]

Completed PHASE3

First recorded

Sep 2003

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

German CLL Study Group

Data source: German CLL Study Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Amberg, Germany , Ansbach, Germany , Augsburg, Germany , Bad Saarow, Germany , Bayreuth, Germany , Berlin, Germany , Bochum, Germany , Bremen, Germany , Cologne, Germany , Cottbus, Germany and 59 more locations