deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT00263588

Lapatinib for Brain Metastases In ErbB2-Positive Breast Cancer

A Phase II Study of Lapatinib for Brain Metastases in Subjects With ErbB2-Positive Breast Cancer Following Trastuzumab-based Systemic Therapy and Cranial Radiotherapy

Sponsor: Novartis Pharmaceuticals

Interventions lapatinib
Updated 11 times since 2017 Last updated: Nov 21, 2019 Started: Dec 2, 2005 Primary completion: Sep 25, 2007 Completion: Mar 15, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00263588, this PHASE2 trial focuses on Neoplasms, Breast and remains completed. Sponsored by Novartis Pharmaceuticals, it has been updated 11 times since 2005, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshotActive Not Recruiting~Jun 2017 – ~Mar 2018 · 9 months · monthly snapshotActive Not Recruiting~Mar 2018 – ~Jun 2018 · 3 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Jan 2020 · 19 months · monthly snapshotCompleted~Jan 2020 – ~Jan 2021 · 12 months · monthly snapshotCompleted~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshotCompleted~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 7 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Dec 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. Jan 2021 — Dec 2021 [monthly]

    Completed PHASE2

Show 6 earlier versions
  1. Jan 2020 — Jan 2021 [monthly]

    Completed PHASE2

  2. Jun 2018 — Jan 2020 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  3. Mar 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

  4. Jun 2017 — Mar 2018 [monthly]

    Active Not Recruiting PHASE2

  5. Feb 2017 — Jun 2017 [monthly]

    Active Not Recruiting PHASE2

  6. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Dec 2005

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Novartis Pharmaceuticals
Data source: Novartis

For direct contact, visit the study record on ClinicalTrials.gov .