deltatrials
Completed PHASE2 INTERVENTIONAL 1-arm NCT00266110

Vaccine Therapy, Trastuzumab, and Vinorelbine in Treating Patients With Locally Recurrent or Metastatic Breast Cancer

Phase II Trial Evaluating the Toxicity and Efficacy of a Multiepitope Dendritic Cell Vaccine Given With Trastuzumab and Vinorelbine Ditartrate for the Treatment of Women With Metastatic Breast Cancer That Express HLA-A0201 and Whose Tumors Overexpress HER-2/NEU

Sponsor: National Cancer Institute (NCI)

Conditions Breast Cancer
Updated 11 times since 2017 Last updated: Aug 14, 2018 Started: Dec 31, 2005 Primary completion: Feb 28, 2013 Completion: Oct 27, 2017
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Breast Cancer, this trial is completed. The trial is conducted by National Cancer Institute (NCI) and has accumulated 11 data snapshots since 2005. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Jul 2017 · 5 months · monthly snapshotActive Not Recruiting~Jul 2017 – ~Jun 2018 · 11 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshotActive Not Recruiting~Jul 2018 – ~Oct 2018 · 3 months · monthly snapshotActive Not Recruiting~Oct 2018 – ~Jan 2021 · 27 months · monthly snapshotCompleted~Jan 2021 – ~Dec 2022 · 23 months · monthly snapshotCompleted~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshotCompleted~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 23 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  3. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE2

  4. Dec 2022 — Jan 2023 [monthly]

    Completed PHASE2

  5. Jan 2021 — Dec 2022 [monthly]

    Completed PHASE2

Show 6 earlier versions
  1. Oct 2018 — Jan 2021 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  2. Jul 2018 — Oct 2018 [monthly]

    Active Not Recruiting PHASE2

  3. Jun 2018 — Jul 2018 [monthly]

    Active Not Recruiting PHASE2

  4. Jul 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

  5. Feb 2017 — Jul 2017 [monthly]

    Active Not Recruiting PHASE2

  6. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Dec 2005

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
  • Susan G. Komen Breast Cancer Foundation
  • UNC Lineberger Comprehensive Cancer Center
Data source: UNC Lineberger Comprehensive Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations