Completed PHASE2/PHASE3 INTERVENTIONAL 2-arm NCT00277355

Pilot Study of Minocycline in Huntington's Disease

A Multi-Center, Double-Blind, Pilot Study of Minocycline in Huntington's Disease

Sponsor: FDA Office of Orphan Products Development

Interventions Matching placebo minocycline

Updated 7 times since 2017 Last updated: Apr 17, 2013 Started: Apr 30, 2006 Primary completion: Oct 31, 2008 Completion: Nov 30, 2008

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00277355, this PHASE2/PHASE3 trial focuses on Huntington Disease and remains completed. Sponsored by FDA Office of Orphan Products Development, it has been updated 7 times since 2006, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE2/PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2/PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2/PHASE3

Phase: PHASE2_PHASE3 → PHASE2/PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE2_PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE2_PHASE3

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE2_PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2_PHASE3

First recorded

Apr 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

FDA Office of Orphan Products Development
Merit Cudkowicz

Data source: Huntington Study Group

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albany, United States , Baltimore, United States , Birmingham, United States , Boston, United States , Englewood, United States , Gainesville, United States , Galveston, United States , New York, United States , Rochester, United States , St Louis, United States and 2 more locations