Evaluation of the Utility of Minocycline as an Anti-Inflammatory Agent in the Treatment of Asthma (Mino)
Sponsor: State University of New York - Downstate Medical Center
Listed as NCT00456677, this PHASE2 trial focuses on Asthma and remains completed. Sponsored by State University of New York - Downstate Medical Center, it has been updated 6 times since 1996, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.
Study Description(click to expand)This is a double-blind, placebo-controlled crossover study of adult asthmatics given minocycline 150 mg po BID or placebo as add-on therapy for eight weeks each. Each eight week arm is separated by a four week wash-out. Spirometry is performed at the baseline and end of each arm. Daily symptoms scores, peak flow rates, and oral steroid requirements are recorded. A standardized asthma quality of life symptoms assessment is made every four weeks (AQLQ, Juniper).
This is a double-blind, placebo-controlled crossover study of adult asthmatics given minocycline 150 mg po BID or placebo as add-on therapy for eight weeks each. Each eight week arm is separated by a four week wash-out. Spirometry is performed at the baseline and end of each arm. Daily symptoms scores, peak flow rates, and oral steroid requirements are recorded. A standardized asthma quality of life symptoms assessment is made every four weeks (AQLQ, Juniper).
Status Flow
Change History
6 versions recorded-
Sep 2024 — Present [monthly]
Completed PHASE2
-
Jul 2024 — Sep 2024 [monthly]
Completed PHASE2
-
Jan 2021 — Jul 2024 [monthly]
Completed PHASE2
-
Jun 2018 — Jan 2021 [monthly]
Completed PHASE2
-
Jun 2017 — Jun 2018 [monthly]
Completed PHASE2
Status: Unknown Status → Completed
▶ Show 1 earlier version
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Jan 2017 — Jun 2017 [monthly]
Unknown Status PHASE2
First recorded
Jun 1996
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- State University of New York - Downstate Medical Center
For direct contact, visit the study record on ClinicalTrials.gov .