deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT00300781

Study Evaluating HKI-272 (Neratinib) In Subjects With Advanced Breast Cancer

Phase 2 Study of HKI-272 In Subjects With Advanced Breast Cancer

Sponsor: Puma Biotechnology, Inc.

Interventions neratinib
Updated 11 times since 2017 Last updated: Aug 10, 2018 Started: Aug 4, 2006 Primary completion: Apr 30, 2008 Completion: Jan 30, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Breast Neoplasms and Neoplasms, this trial is completed. The trial is conducted by Puma Biotechnology, Inc. and has accumulated 11 data snapshots since 2006. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~Oct 2017 · 8 months · monthly snapshotActive Not Recruiting~Oct 2017 – ~Jun 2018 · 8 months · monthly snapshotActive Not Recruiting~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshotActive Not Recruiting~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshotActive Not Recruiting~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshotCompleted~Sep 2018 – ~Jan 2021 · 28 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. Sep 2018 — Jan 2021 [monthly]

    Completed PHASE2

Show 6 earlier versions
  1. Aug 2018 — Sep 2018 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  2. Jul 2018 — Aug 2018 [monthly]

    Active Not Recruiting PHASE2

  3. Jun 2018 — Jul 2018 [monthly]

    Active Not Recruiting PHASE2

  4. Oct 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

  5. Feb 2017 — Oct 2017 [monthly]

    Active Not Recruiting PHASE2

  6. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Aug 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Puma Biotechnology, Inc.
Data source: Puma Biotechnology, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .