deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 3-arm NCT00398567

A Phase 1/2 Study Of HKI-272 (Neratinib) in Combination With Trastuzumab (Herceptin) In Subjects With Advanced Breast Cancer

A Phase I/II Study of HKI-272 in Combination With Trastuzumab (Herceptin) in Subjects With Advanced Breast Cancer

Sponsor: Puma Biotechnology, Inc.

Updated 8 times since 2017 Last updated: Jun 26, 2018 Started: Apr 4, 2007 Primary completion: Jul 31, 2009 Completion: Mar 2, 2018
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00398567, this PHASE1/PHASE2 trial focuses on Advanced Breast Cancer and remains completed. Sponsored by Puma Biotechnology, Inc., it has been updated 8 times since 2007, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotActive Not Recruiting~Feb 2017 – ~May 2018 · 15 months · monthly snapshotActive Not Recruiting~May 2018 – ~Jun 2018 · 31 days · monthly snapshotActive Not Recruiting~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshotActive Not Recruiting~Aug 2018 – ~Jan 2021 · 29 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

  4. Aug 2018 — Jan 2021 [monthly]

    Completed PHASE1_PHASE2

    Status: Active Not RecruitingCompleted

  5. Jun 2018 — Aug 2018 [monthly]

    Active Not Recruiting PHASE1_PHASE2

Show 3 earlier versions
  1. May 2018 — Jun 2018 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  2. Feb 2017 — May 2018 [monthly]

    Active Not Recruiting PHASE1_PHASE2

  3. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    First recorded

Apr 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Puma Biotechnology, Inc.
Data source: Puma Biotechnology, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .