Safety of TKI258 in Advanced/Metastatic Melanoma Subjects
A Phase I/II Dose Escalating Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of TKI258 (CHIR-258) in Patients With Locally Advanced or Metastatic Melanoma
Sponsor: Novartis Pharmaceuticals
Listed as NCT00303251, this PHASE1/PHASE2 trial focuses on Melanoma and remains completed. Sponsored by Novartis Pharmaceuticals, it has been updated 8 times since 2006, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.
Status Flow
Change History
8 versions recorded-
Sep 2024 — Present [monthly]
Completed PHASE1/PHASE2
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Jul 2024 — Sep 2024 [monthly]
Completed PHASE1/PHASE2
Phase: PHASE1_PHASE2 → PHASE1/PHASE2
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Apr 2022 — Jul 2024 [monthly]
Completed PHASE1_PHASE2
-
Apr 2021 — Apr 2022 [monthly]
Completed PHASE1_PHASE2
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Jan 2021 — Apr 2021 [monthly]
Completed PHASE1_PHASE2
▶ Show 3 earlier versions
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Jun 2018 — Jan 2021 [monthly]
Completed PHASE1_PHASE2
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Feb 2017 — Jun 2018 [monthly]
Completed PHASE1_PHASE2
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Jan 2017 — Feb 2017 [monthly]
Completed PHASE1_PHASE2
First recorded
Apr 2006
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Novartis Pharmaceuticals
For direct contact, visit the study record on ClinicalTrials.gov .