Completed PHASE2 INTERVENTIONAL 2-arm NCT00790426

Phase II Study of TKI258 in Advanced Urothelial Carcinoma

A Phase II Multi-center, Non-randomized, Open Label Study of TKI258 in FGFR3 Mutated and FGFR3 Wild Type Advanced Urothelial Carcinoma

Sponsor: Novartis Pharmaceuticals

Conditions Urothelial Cancer

Interventions TKI258

Updated 11 times since 2017 Last updated: Dec 11, 2020 Started: Mar 31, 2010 Primary completion: Apr 30, 2012 Completion: Apr 30, 2012

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Urothelial Cancer, this trial is completed. The trial is conducted by Novartis Pharmaceuticals and has accumulated 11 data snapshots since 2010. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

Change History

11 versions recorded

Dec 2025 — Present [monthly]

Completed PHASE2
Sep 2025 — Dec 2025 [monthly]

Completed PHASE2
Sep 2024 — Sep 2025 [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Apr 2022 — Jul 2024 [monthly]

Completed PHASE2

▶ Show 6 earlier versions

Jan 2021 — Apr 2022 [monthly]

Completed PHASE2
Oct 2020 — Jan 2021 [monthly]

Completed PHASE2
Sep 2020 — Oct 2020 [monthly]

Completed PHASE2
Jun 2018 — Sep 2020 [monthly]

Completed PHASE2
Feb 2017 — Jun 2018 [monthly]

Completed PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2

First recorded

Mar 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Novartis Pharmaceuticals

Data source: Novartis

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Barcelona, Spain , Berlin, Germany , Boston, United States , Chicago, United States , Dresden, Germany , Durham, United States , La Jolla, United States , Las Vegas, United States , Leeds, United Kingdom , Los Angeles, United States and 12 more locations