deltatrials
Terminated PHASE3 NCT00303628

Postoperative Chemotherapy With or Without Bevacizumab for Patients With Stage II or III Rectal Cancer

Intergroup Randomized Phase III Study of Postoperative Oxaliplatin, 5-Fluorouracil and Leucovorin vs Oxaliplatin, 5-Fluorouracil, Leucovorin and Bevacizumab for Patients With Stage II or III Rectal Cancer Receiving Pre-operative Chemoradiation

Sponsor: ECOG-ACRIN Cancer Research Group

Updated 9 times since 2017 Last updated: Jun 20, 2023 Started: May 11, 2006 Primary completion: Apr 30, 2015 Completion: Feb 11, 2019

A PHASE3 clinical study on Adenocarcinoma of the Rectum and Stage II Rectal Cancer, this trial is terminated or withdrawn. The trial is conducted by ECOG-ACRIN Cancer Research Group and has accumulated 9 data snapshots since 2006. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotTerminated~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotTerminated~Jun 2018 – ~Dec 2020 · 30 months · monthly snapshotTerminated~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotTerminated~Jan 2021 – ~Aug 2023 · 31 months · monthly snapshotTerminated~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 7 months · monthly snapshotTerminated

Change History

9 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  4. Aug 2023 — Jul 2024 [monthly]

    Terminated PHASE3

  5. Jan 2021 — Aug 2023 [monthly]

    Terminated PHASE3

Show 4 earlier versions
  1. Dec 2020 — Jan 2021 [monthly]

    Terminated PHASE3

  2. Jun 2018 — Dec 2020 [monthly]

    Terminated PHASE3

  3. Feb 2017 — Jun 2018 [monthly]

    Terminated PHASE3

  4. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE3

    First recorded

May 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • ECOG-ACRIN Cancer Research Group
  • National Cancer Institute (NCI)
Data source: Eastern Cooperative Oncology Group

For direct contact, visit the study record on ClinicalTrials.gov .