Completed PHASE2 INTERVENTIONAL 2-arm NCT00308516

5-Fluorouracil, Bevacizumab, and Radiation Followed by Modified FOLFOX6 and Bevacizumab in Stage II/III Rectal Cancer

A Phase II Study of 5-Fluorouracil, Bevacizumab (Avastin), and Radiation in the Preoperative or Adjuvant Treatment of Patients With Stage II / III Rectal Cancer

Sponsor: Genentech, Inc.

Conditions Cancer of the Rectum Colorectal Cancer Rectal Cancer

Interventions 5-Fluorouracil Bevacizumab Leucovorin Oxaliplatin Radiation Therapy

Updated 7 times since 2017 Last updated: Nov 11, 2021 Started: Mar 31, 2006 Primary completion: Apr 30, 2009 Completion: Feb 29, 2012

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00308516, this PHASE2 trial focuses on Cancer of the Rectum and Colorectal Cancer and remains completed. Sponsored by Genentech, Inc., it has been updated 7 times since 2006, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

Change History

7 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE2
Jul 2024 — Sep 2024 [monthly]

Completed PHASE2
Jan 2022 — Jul 2024 [monthly]

Completed PHASE2
Jan 2021 — Jan 2022 [monthly]

Completed PHASE2
Jun 2018 — Jan 2021 [monthly]

Completed PHASE2

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE2
Jan 2017 — Feb 2017 [monthly]

Completed PHASE2

First recorded

Mar 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Genentech, Inc.
SCRI Development Innovations, LLC

Data source: SCRI Development Innovations, LLC

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Anniston, United States , Chattanooga, United States , Drexel Hill, United States , Fort Myers, United States , Gainesville, United States , Jacksonville, United States , Jonesboro, United States , Lakeland, United States , Louisville, United States , Marietta, United States and 4 more locations