Completed PHASE4 INTERVENTIONAL 4-arm NCT00315146

Optimizing Body Composition for Function in Older Adults

Optimizing Body Composition for Function in Older Adults (OPTIMA) - A Pepper Pilot Study

Sponsor: National Institute on Aging (NIA)

Conditions Obesity Overweight With Indications for Weight Loss

Interventions Hypocaloric diet Pioglitazone Placebo Resistance exercise training to maximize muscle power

Updated 9 times since 2017 Last updated: Jul 30, 2018 Started: Apr 30, 2006 Primary completion: Apr 30, 2007 Completion: Apr 30, 2007

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00315146, this PHASE4 trial focuses on Obesity and Overweight With Indications for Weight Loss and remains completed. Sponsored by National Institute on Aging (NIA), it has been updated 9 times since 2006, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

9 versions recorded

Sep 2024 — Present [monthly]

Completed PHASE4
Jul 2024 — Sep 2024 [monthly]

Completed PHASE4
Jan 2023 — Jul 2024 [monthly]

Completed PHASE4
Dec 2022 — Jan 2023 [monthly]

Completed PHASE4
Jan 2021 — Dec 2022 [monthly]

Completed PHASE4

▶ Show 4 earlier versions

Sep 2018 — Jan 2021 [monthly]

Completed PHASE4
Aug 2018 — Sep 2018 [monthly]

Completed PHASE4
Jun 2018 — Aug 2018 [monthly]

Completed PHASE4
Jan 2017 — Jun 2018 [monthly]

Completed PHASE4

First recorded

Apr 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

National Institute on Aging (NIA)
Takeda Pharmaceuticals North America, Inc.
Wake Forest University Health Sciences

Data source: Wake Forest University Health Sciences

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Winston-Salem, United States