deltatrials
Completed PHASE3 INTERVENTIONAL 4-arm NCT00320099

Combination of Corticotherapy and Intensive Insulin Therapy for Septic Shock (COIITSS)

Phase 3 Study of Corticotherapy (Hydrocortisone Alone Versus Hydrocortisone Plus Fludrocortisone) Versus Corticotherapy Plus Intensive Insulin Therapy for Septic Shock

Sponsor: Assistance Publique - Hôpitaux de Paris

Conditions Septic Shock
Interventions Hydrocortisone fludrocortisone hydrocortisone recombinant human insulin
Updated 6 times since 2017 Last updated: Apr 5, 2010 Started: Jan 31, 2006 Primary completion: Jan 31, 2009 Completion: Feb 28, 2009
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00320099, this PHASE3 trial focuses on Septic Shock and remains completed. Sponsored by Assistance Publique - Hôpitaux de Paris, it has been updated 6 times since 2006, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

6 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE3

▶ Show 1 earlier version

  1. Jan 2017 — Jun 2018 [monthly]

    Completed PHASE3

    First recorded

Jan 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Assistance Publique - Hôpitaux de Paris
  • University of Versailles
Data source: University of Versailles

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations