deltatrials
Completed PHASE3 NCT00357994

Study of Efficacy, Safety and Tolerability of Levodopa-Carbidopa Intestinal Gel in Levodopa-Responsive Parkinson's Subjects

A Randomized, Double-Blind, Double-Dummy, Efficacy, Safety and Tolerability Study of Levodopa - Carbidopa Intestinal Gel in Levodopa-Responsive Parkinson's Subjects Receiving Optimized Treatments With Parkinson Medicinal Products Who Continue to Experience Persistent Motor Fluctuations

Sponsor: AbbVie (prior sponsor, Abbott)

Conditions Advanced Parkinson's Disease
Interventions CADD-Legacy® 1400 ambulatory infusion pump J-tube Levodopa carbidopa (LC) oral encapsulated immediate release (IR) tablets Levodopa carbidopa intestinal gel (LCIG) PEG tube Placebo (PBO) oral capsules Placebo gel
Updated 7 times since 2017 Last updated: Jan 12, 2015 Started: Jan 31, 2009 Primary completion: Oct 31, 2011 Completion: Oct 31, 2011

A PHASE3 clinical study on Advanced Parkinson's Disease, this trial is completed. The trial is conducted by AbbVie (prior sponsor, Abbott) and has accumulated 7 data snapshots since 2009. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Change History

7 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jun 2018 — Jan 2021 [monthly]

    Completed PHASE3

▶ Show 2 earlier versions

  1. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE3

  2. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE3

    First recorded

Jan 2009

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • AbbVie (prior sponsor, Abbott)
  • Quintiles, Inc.
Data source: AbbVie

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Baltimore, United States, Bochum, Germany, Bradenton, United States, Bremerhaven, Germany, Burlington, United States, Dresden, Germany, Englewood, United States, Gainesville, United States, Hanover, Germany, Kiel, Germany and 5 more location s