deltatrials
Completed PHASE2 NCT00376688

Temsirolimus in Treating Patients With Locally Advanced or Metastatic Breast Cancer

Phase II Trial of CCI-779 (Temsirolimus) in Patients With Locally Advanced or Metastatic Breast Cancer

Sponsor: National Cancer Institute (NCI)

Conditions Recurrent Breast Carcinoma Stage III Breast Cancer AJCC v7 Stage IIIA Breast Cancer AJCC v7 Stage IIIB Breast Cancer AJCC v7 Stage IIIC Breast Cancer AJCC v7 Stage IV Breast Cancer AJCC v6 and v7
Interventions Laboratory Biomarker Analysis Temsirolimus
Updated 18 times since 2017 Last updated: Feb 13, 2020 Started: Jul 11, 2006 Primary completion: Jun 12, 2008 Completion: Dec 16, 2019

Listed as NCT00376688, this PHASE2 trial focuses on Recurrent Breast Carcinoma and Stage III Breast Cancer AJCC v7 and remains completed. Sponsored by National Cancer Institute (NCI), it has been updated 18 times since 2006, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Change History

18 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. Mar 2020 — Jan 2021 [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

▶ Show 13 earlier versions

  1. Jan 2020 — Mar 2020 [monthly]

    Active Not Recruiting PHASE2

  2. Oct 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE2

  3. Sep 2019 — Oct 2019 [monthly]

    Active Not Recruiting PHASE2

  4. Jun 2019 — Sep 2019 [monthly]

    Active Not Recruiting PHASE2

  5. Mar 2019 — Jun 2019 [monthly]

    Active Not Recruiting PHASE2

  6. Dec 2018 — Mar 2019 [monthly]

    Active Not Recruiting PHASE2

  7. Jul 2018 — Dec 2018 [monthly]

    Active Not Recruiting PHASE2

  8. Jun 2018 — Jul 2018 [monthly]

    Active Not Recruiting PHASE2

  9. Dec 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE2

  10. Nov 2017 — Dec 2017 [monthly]

    Active Not Recruiting PHASE2

  11. Jul 2017 — Nov 2017 [monthly]

    Active Not Recruiting PHASE2

  12. Feb 2017 — Jul 2017 [monthly]

    Active Not Recruiting PHASE2

  13. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE2

    First recorded

Jul 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • National Cancer Institute (NCI)
Data source: National Cancer Institute (NCI)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

  • • Chicago, United States
  • • St Louis, United States