deltatrials
Completed NA INTERVENTIONAL 2-arm NCT00446381

Effect of Macugen(Pegaptanib)on Surgical Outcomes and VEGF Levels in Diabetic Patients With PDR (Diabetic Retinopathy or CSDME (Macular Edema) (PEGAP001)

Effect of Macugen (Pegaptanib) on Surgical Outcomes and Growth Factors Including Vascular Endothelial Growth Factor (VEGF) Levels in Patients With Proliferative Diabetic Retinopathy (PDR) and Clinically Significant Diabetic Macular Edema (CSDME)

Sponsor: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

Updated 7 times since 2017 Last updated: Apr 17, 2012 Started: Oct 31, 2006 Primary completion: Sep 30, 2008 Completion: Sep 30, 2008
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00446381, this NA trial focuses on Diabetic Macular Edema and Proliferative Diabetic Retinopathy and remains completed. Sponsored by London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's, it has been updated 7 times since 2006, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotCompleted~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshotCompleted~Jan 2025 – ~Apr 2025 · 3 months · monthly snapshotCompleted~Apr 2025 – present · 17 months · monthly snapshotCompleted

Change History

7 versions recorded
  1. Apr 2025 — Present [monthly]

    Completed NA

  2. Jan 2025 — Apr 2025 [monthly]

    Completed NA

  3. Sep 2024 — Jan 2025 [monthly]

    Completed NA

  4. Jul 2024 — Sep 2024 [monthly]

    Completed NA

  5. Jan 2021 — Jul 2024 [monthly]

    Completed NA

Show 2 earlier versions
  1. Jun 2018 — Jan 2021 [monthly]

    Completed NA

  2. Jan 2017 — Jun 2018 [monthly]

    Completed NA

    First recorded

Oct 2006

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
  • Pfizer
Data source: London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations