Completed PHASE3 INTERVENTIONAL 3-arm NCT00445003

Laser-Ranibizumab-Triamcinolone for Proliferative Diabetic Retinopathy (LRTforDME+PRP)

Intravitreal Ranibizumab or Triamcinolone Acetonide as Adjunctive Treatment to Panretinal Photocoagulation for Proliferative Diabetic Retinopathy

Sponsor: Allergan

Conditions Diabetic Macular Edema Proliferative Diabetic Retinopathy

Interventions Focal/grid laser Ranibizumab Sham injection Triamcinolone Acetonide

Updated 7 times since 2017 Last updated: Aug 25, 2016 Started: Mar 31, 2007 Primary completion: Oct 31, 2009 Completion: Jul 31, 2010

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Diabetic Macular Edema and Proliferative Diabetic Retinopathy, this trial is completed. The trial is conducted by Allergan and has accumulated 7 data snapshots since 2007. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Mar 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Allergan
Genentech, Inc.
Jaeb Center for Health Research
National Eye Institute (NEI)

Data source: Jaeb Center for Health Research

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Abilene, United States , Arlington, United States , Artesia, United States , Augusta, United States , Austin, United States , Baltimore, United States , Bangor, United States , Beverly Hills, United States , Boston, United States , Chapel Hill, United States and 39 more locations