Completed PHASE4 INTERVENTIONAL 2-arm NCT00470834

Prostate Cancer Study In Men Who Have Failed First-Line Androgen Deprivation Therapy

A Randomized Double-Blind Parallel Group Study Comparing Casodex (or Generic Equivalent) 50mg Plus Placebo to Casodex (or Generic Equivalent) 50mg Plus Dutasteride 3.5mg Administered for 18 Months to Men With Prostate Cancer Who Have Failed First-Line Androgen Deprivation Therapy (Assessed by Rising PSA) Followed by a Two-Year Extension Phase

Sponsor: GlaxoSmithKline

Conditions Neoplasms, Prostate

Interventions bicalutamide dutasteride placebo

Updated 7 times since 2017 Last updated: Jan 12, 2017 Started: May 31, 2007 Primary completion: Feb 28, 2013 Completion: Feb 28, 2013

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00470834, this PHASE4 trial focuses on Neoplasms, Prostate and remains completed. Sponsored by GlaxoSmithKline, it has been updated 7 times since 2007, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE4
Sep 2024 — Sep 2025 [monthly]

Completed PHASE4
Jul 2024 — Sep 2024 [monthly]

Completed PHASE4
Jan 2021 — Jul 2024 [monthly]

Completed PHASE4
Jun 2018 — Jan 2021 [monthly]

Completed PHASE4

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE4
Jan 2017 — Feb 2017 [monthly]

Completed PHASE4

First recorded

May 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

GlaxoSmithKline

Data source: GlaxoSmithKline

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Albany, United States , Anaheim, United States , Annapolis, United States , Aventura, United States , Bala-Cynwyd, United States , Barrie, Canada , Burlington, Canada , Calgary, Canada , Chaska, United States , Columbus, United States and 50 more locations