deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT00477282

Karenitecin Versus Topotecan in Patients With Advanced Epithelial Ovarian Cancer

A Phase 3 Study of Safety and Efficacy of Karenitecin Versus Topotecan Administered for 5 Consecutive Days Every 3 Weeks in Patients With Advanced Epithelial Ovarian Cancer

Sponsor: BioNumerik Pharmaceuticals, Inc.

Conditions Ovarian Cancer
Updated 11 times since 2017 Last updated: Mar 10, 2020 Started: Aug 31, 2007 Primary completion: Jun 30, 2013 Completion: Jun 30, 2013
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Ovarian Cancer and is currently completed. BioNumerik Pharmaceuticals, Inc. leads this study, which shows 11 recorded versions since 2007 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotCompleted~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshotCompleted~Nov 2018 – ~Aug 2019 · 9 months · monthly snapshotCompleted~Aug 2019 – ~Apr 2020 · 8 months · monthly snapshotCompleted~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshotCompleted~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshotCompleted~Oct 2021 – ~Jul 2024 · 33 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 11 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Oct 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Jan 2021 — Oct 2021 [monthly]

    Completed PHASE3

Show 6 earlier versions
  1. Apr 2020 — Jan 2021 [monthly]

    Completed PHASE3

  2. Aug 2019 — Apr 2020 [monthly]

    Completed PHASE3

  3. Nov 2018 — Aug 2019 [monthly]

    Completed PHASE3

  4. Jun 2018 — Nov 2018 [monthly]

    Completed PHASE3

  5. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE3

  6. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE3

    First recorded

Aug 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • BioNumerik Pharmaceuticals, Inc.
  • Crown Bioscience
Data source: BioNumerik Pharmaceuticals, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .