Safety and Efficacy of Folfox4 + Weekly Cetuximab vs Folfox 4+Biweekly Cetuximab by Metastatic Colorectal Cancer (CORE 2)
A Randomized, Open-label Phase II Study Evaluating the Efficacy and Safety of FOLFOX4 + Weekly Cetuximab Versus FOLFOX4+ Biweekly Cetuximab as First-line Therapy in Patients With Metastatic Colorectal Cancer.
Sponsor: Central European Cooperative Oncology Group
A PHASE2 clinical study on Colorectal Cancer, this trial is completed. The trial is conducted by Central European Cooperative Oncology Group and has accumulated 6 data snapshots since 2008. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.
Status Flow
Change History
6 versions recorded-
Sep 2025 — Present [monthly]
Completed PHASE2
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Sep 2024 — Sep 2025 [monthly]
Completed PHASE2
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Jul 2024 — Sep 2024 [monthly]
Completed PHASE2
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Jan 2021 — Jul 2024 [monthly]
Completed PHASE2
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Jun 2018 — Jan 2021 [monthly]
Completed PHASE2
▶ Show 1 earlier version
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Jan 2017 — Jun 2018 [monthly]
Completed PHASE2
First recorded
Jan 2008
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Central European Cooperative Oncology Group
For direct contact, visit the study record on ClinicalTrials.gov .
Study Locations
Athens, Greece , Belgrade, Serbia , Bratislava, Slovakia , Bucharest, Romania , Budapest, Hungary , Cluj-Napoca, Romania , Kamenitz, Serbia , Kfar Saba, Israel , Leoben, Austria , Ljubljana, Slovenia and 9 more locations