deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT00562497

Efficacy and Safety of Prochymal® Infusion in Combination With Corticosteroids for the Treatment of Newly Diagnosed Acute Graft Versus Host Disease (GVHD)

A Phase III, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Prochymal® Infusion in Combination With Corticosteroids for the Treatment of Newly Diagnosed Acute GVHD

Sponsor: Mesoblast, Inc.

Updated 11 times since 2017 Last updated: Jan 14, 2022 Started: Jan 31, 2008 Primary completion: Jul 14, 2009 Completion: May 20, 2010
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Graft Versus Host Disease and is currently completed. Mesoblast, Inc. leads this study, which shows 11 recorded versions since 2008 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotCompleted~Jun 2018 – ~Apr 2020 · 22 months · monthly snapshotCompleted~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshotCompleted~Jan 2021 – ~Jan 2022 · 12 months · monthly snapshotCompleted~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshotCompleted~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshotCompleted~Apr 2022 – ~Jul 2024 · 27 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Apr 2022 — Jul 2024 [monthly]

    Completed PHASE3

  5. Feb 2022 — Apr 2022 [monthly]

    Completed PHASE3

Show 6 earlier versions
  1. Jan 2022 — Feb 2022 [monthly]

    Completed PHASE3

  2. Jan 2021 — Jan 2022 [monthly]

    Completed PHASE3

  3. Apr 2020 — Jan 2021 [monthly]

    Completed PHASE3

  4. Jun 2018 — Apr 2020 [monthly]

    Completed PHASE3

  5. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE3

  6. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE3

    First recorded

Jan 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Mesoblast, Inc.
Data source: Mesoblast, Ltd.

For direct contact, visit the study record on ClinicalTrials.gov .