deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT00683722

PROCHYMAL™ (Human Adult Stem Cells) for the Treatment of Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

A Phase II, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of PROCHYMAL™ (ex Vivo Cultured Adult Human Mesenchymal Stem Cells) Intravenous Infusion for the Treatment of Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Sponsor: Mesoblast, Inc.

Updated 10 times since 2017 Last updated: Mar 9, 2026 Started: Mar 20, 2008 Primary completion: Mar 9, 2009 Completion: Aug 24, 2010
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Chronic Bronchitis and Pulmonary Disease, Chronic Obstructive, this trial is completed. The trial is conducted by Mesoblast, Inc. and has accumulated 10 data snapshots since 2008. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotCompleted~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshotCompleted~Jun 2018 – ~Apr 2020 · 22 months · monthly snapshotCompleted~Apr 2020 – ~Jan 2021 · 9 months · monthly snapshotCompleted~Jan 2021 – ~Jan 2022 · 12 months · monthly snapshotCompleted~Jan 2022 – ~Apr 2022 · 3 months · monthly snapshotCompleted~Apr 2022 – ~Jul 2024 · 27 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Mar 2026 · 18 months · monthly snapshotCompleted~Mar 2026 – present · 4 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Mar 2026 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Mar 2026 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Apr 2022 — Jul 2024 [monthly]

    Completed PHASE2

  5. Jan 2022 — Apr 2022 [monthly]

    Completed PHASE2

Show 5 earlier versions
  1. Jan 2021 — Jan 2022 [monthly]

    Completed PHASE2

  2. Apr 2020 — Jan 2021 [monthly]

    Completed PHASE2

  3. Jun 2018 — Apr 2020 [monthly]

    Completed PHASE2

  4. Feb 2017 — Jun 2018 [monthly]

    Completed PHASE2

  5. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE2

    First recorded

Mar 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Mesoblast, Inc.
Data source: Mesoblast, Ltd.

For direct contact, visit the study record on ClinicalTrials.gov .