deltatrials
Completed PHASE2 NCT00592553

Phase 2B Study of PTC124 (Ataluren) in Duchenne/Becker Muscular Dystrophy (DMD/BMD)

A Phase 2B Efficacy and Safety Study of PTC124 in Subjects With Nonsense-Mutation-Mediated Duchenne and Becker Muscular Dystrophy

Sponsor: PTC Therapeutics

Interventions Ataluren Placebo
Updated 10 times since 2017 Last updated: Mar 26, 2020 Started: Feb 29, 2008 Primary completion: Dec 31, 2009 Completion: Dec 31, 2009

Listed as NCT00592553, this PHASE2 trial focuses on Becker Muscular Dystrophy and Duchenne Muscular Dystrophy and remains completed. Sponsored by PTC Therapeutics, it has been updated 10 times since 2008, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. May 2020 — Jan 2021 [monthly]

    Completed PHASE2

Show 5 earlier versions
  1. Jun 2018 — May 2020 [monthly]

    Completed PHASE2

  2. Dec 2017 — Jun 2018 [monthly]

    Completed PHASE2

    Phase: PHASE2_PHASE3PHASE2

  3. Aug 2017 — Dec 2017 [monthly]

    Completed PHASE2_PHASE3

  4. Feb 2017 — Aug 2017 [monthly]

    Completed PHASE2_PHASE3

  5. Jan 2017 — Feb 2017 [monthly]

    Completed PHASE2_PHASE3

    First recorded

Feb 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • PTC Therapeutics
Data source: PTC Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aurora, United States, Barcelona, Spain, Boston, United States, Calgary, Canada, Cincinnati, United States, Dallas, United States, Durham, United States, Essen, Germany, Freiburg im Breisgau, Germany, Gothenburg, Sweden and 26 more location s