deltatrials
Completed PHASE3 INTERVENTIONAL 1-arm NCT01247207

Study of Ataluren in Previously Treated Participants With Nonsense Mutation Dystrophinopathy (nmDBMD)

An Open-Label, Safety Study for Ataluren (PTC124) Patients With Nonsense Mutation Dystrophinopathy

Sponsor: PTC Therapeutics

Conditions Duchenne Muscular Dystrophy
Interventions Ataluren
Updated 50 times since 2017 Last updated: Mar 5, 2026 Started: Nov 30, 2010 Primary completion: Feb 10, 2026 Completion: Feb 10, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01247207, this PHASE3 trial focuses on Duchenne Muscular Dystrophy and remains completed. Sponsored by PTC Therapeutics, it has been updated 50 times since 2010, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2017 · 4 months · monthly snapshot~Jun 2017 – ~May 2018 · 11 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Dec 2018 · 6 months · monthly snapshot~Dec 2018 – ~Apr 2019 · 4 months · monthly snapshot~Apr 2019 – ~Jun 2019 · 2 months · monthly snapshot~Jun 2019 – ~Aug 2019 · 2 months · monthly snapshot~Aug 2019 – ~Nov 2019 · 3 months · monthly snapshot~Nov 2019 – ~Jan 2020 · 2 months · monthly snapshot~Jan 2020 – ~Mar 2020 · 2 months · monthly snapshot~Mar 2020 – ~May 2020 · 2 months · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Oct 2020 · 3 months · monthly snapshot~Oct 2020 – ~Dec 2020 · 2 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~Jun 2021 · 2 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Dec 2021 · 2 months · monthly snapshot~Dec 2021 – ~Feb 2022 · 2 months · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~Jun 2022 · 2 months · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Mar 2023 · 59 days · monthly snapshot~Mar 2023 – ~Oct 2023 · 7 months · monthly snapshot~Oct 2023 – ~Dec 2023 · 2 months · monthly snapshot~Dec 2023 – ~Feb 2024 · 2 months · monthly snapshot~Feb 2024 – ~Apr 2024 · 2 months · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Dec 2024 · 30 days · monthly snapshot~Dec 2024 – ~Feb 2025 · 2 months · monthly snapshot~Feb 2025 – ~Apr 2025 · 59 days · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Sep 2025 · 4 months · monthly snapshot~Sep 2025 – ~Mar 2026 · 6 months · monthly snapshot~Mar 2026 – present · 5 months · monthly snapshot

Change History

50 versions recorded

  1. Mar 2026 — Present [monthly]

    Completed PHASE3

    Status: Enrolling By Invitation → Completed

  2. Sep 2025 — Mar 2026 [monthly]

    Enrolling By Invitation PHASE3

  3. May 2025 — Sep 2025 [monthly]

    Enrolling By Invitation PHASE3

  4. Apr 2025 — May 2025 [monthly]

    Enrolling By Invitation PHASE3

  5. Feb 2025 — Apr 2025 [monthly]

    Enrolling By Invitation PHASE3

▶ Show 45 earlier versions

  1. Dec 2024 — Feb 2025 [monthly]

    Enrolling By Invitation PHASE3

  2. Nov 2024 — Dec 2024 [monthly]

    Enrolling By Invitation PHASE3

  3. Oct 2024 — Nov 2024 [monthly]

    Enrolling By Invitation PHASE3

  4. Sep 2024 — Oct 2024 [monthly]

    Enrolling By Invitation PHASE3

  5. Aug 2024 — Sep 2024 [monthly]

    Enrolling By Invitation PHASE3

  6. Jul 2024 — Aug 2024 [monthly]

    Enrolling By Invitation PHASE3

  7. May 2024 — Jul 2024 [monthly]

    Enrolling By Invitation PHASE3

  8. Apr 2024 — May 2024 [monthly]

    Enrolling By Invitation PHASE3

  9. Feb 2024 — Apr 2024 [monthly]

    Enrolling By Invitation PHASE3

  10. Dec 2023 — Feb 2024 [monthly]

    Enrolling By Invitation PHASE3

  11. Oct 2023 — Dec 2023 [monthly]

    Enrolling By Invitation PHASE3

  12. Mar 2023 — Oct 2023 [monthly]

    Enrolling By Invitation PHASE3

  13. Jan 2023 — Mar 2023 [monthly]

    Enrolling By Invitation PHASE3

  14. Dec 2022 — Jan 2023 [monthly]

    Enrolling By Invitation PHASE3

  15. Sep 2022 — Dec 2022 [monthly]

    Enrolling By Invitation PHASE3

  16. Jul 2022 — Sep 2022 [monthly]

    Enrolling By Invitation PHASE3

  17. Jun 2022 — Jul 2022 [monthly]

    Enrolling By Invitation PHASE3

  18. Apr 2022 — Jun 2022 [monthly]

    Enrolling By Invitation PHASE3

  19. Mar 2022 — Apr 2022 [monthly]

    Enrolling By Invitation PHASE3

  20. Feb 2022 — Mar 2022 [monthly]

    Enrolling By Invitation PHASE3

  21. Dec 2021 — Feb 2022 [monthly]

    Enrolling By Invitation PHASE3

  22. Oct 2021 — Dec 2021 [monthly]

    Enrolling By Invitation PHASE3

  23. Sep 2021 — Oct 2021 [monthly]

    Enrolling By Invitation PHASE3

  24. Jun 2021 — Sep 2021 [monthly]

    Enrolling By Invitation PHASE3

  25. Apr 2021 — Jun 2021 [monthly]

    Enrolling By Invitation PHASE3

  26. Mar 2021 — Apr 2021 [monthly]

    Enrolling By Invitation PHASE3

  27. Feb 2021 — Mar 2021 [monthly]

    Enrolling By Invitation PHASE3

  28. Jan 2021 — Feb 2021 [monthly]

    Enrolling By Invitation PHASE3

  29. Dec 2020 — Jan 2021 [monthly]

    Enrolling By Invitation PHASE3

  30. Oct 2020 — Dec 2020 [monthly]

    Enrolling By Invitation PHASE3

  31. Jul 2020 — Oct 2020 [monthly]

    Enrolling By Invitation PHASE3

  32. Jun 2020 — Jul 2020 [monthly]

    Enrolling By Invitation PHASE3

  33. May 2020 — Jun 2020 [monthly]

    Enrolling By Invitation PHASE3

  34. Mar 2020 — May 2020 [monthly]

    Enrolling By Invitation PHASE3

  35. Jan 2020 — Mar 2020 [monthly]

    Enrolling By Invitation PHASE3

  36. Nov 2019 — Jan 2020 [monthly]

    Enrolling By Invitation PHASE3

  37. Aug 2019 — Nov 2019 [monthly]

    Enrolling By Invitation PHASE3

  38. Jun 2019 — Aug 2019 [monthly]

    Enrolling By Invitation PHASE3

  39. Apr 2019 — Jun 2019 [monthly]

    Enrolling By Invitation PHASE3

  40. Dec 2018 — Apr 2019 [monthly]

    Enrolling By Invitation PHASE3

  41. Jun 2018 — Dec 2018 [monthly]

    Enrolling By Invitation PHASE3

  42. May 2018 — Jun 2018 [monthly]

    Enrolling By Invitation PHASE3

  43. Jun 2017 — May 2018 [monthly]

    Enrolling By Invitation PHASE3

  44. Feb 2017 — Jun 2017 [monthly]

    Enrolling By Invitation PHASE3

  45. Jan 2017 — Feb 2017 [monthly]

    Enrolling By Invitation PHASE3

    First recorded

Nov 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • PTC Therapeutics
Data source: PTC Therapeutics

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Ann Arbor, United States , Atlanta, United States , Aurora, United States , Boston, United States , Calgary, Canada , Chicago, United States , Cincinnati, United States , Columbus, United States , Dallas, United States , Durham, United States and 23 more locations