Completed PHASE3 INTERVENTIONAL 2-arm NCT00597584

Safety & Efficacy of Peginesatide for Maintenance Treatment of Anemia in Participants With Chronic Kidney Disease on Hemodialysis (EMERALD 2)

AFX01-14: A Phase 3, Randomized, Active-controlled, Open-label, Multi-center Study of the Safety and Efficacy of Peginesatide for the Maintenance Treatment of Anemia in Hemodialysis Patients Previously Treated With Epoetin

Sponsor: Affymax

Conditions Anemia Chronic Kidney Disease Chronic Renal Failure

Interventions Epoetin alfa or Epoetin beta peginesatide

Updated 7 times since 2017 Last updated: Mar 6, 2013 Started: Oct 31, 2007 Primary completion: Jul 31, 2009 Completion: Jan 31, 2010

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT00597584, this PHASE3 trial focuses on Anemia and Chronic Kidney Disease and remains completed. Sponsored by Affymax, it has been updated 7 times since 2007, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Oct 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Affymax
Takeda

Data source: Affymax

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Alicante, Spain , Amiens, France , Arlington, United States , Asheville, United States , Bakersfield, United States , Barcelona, Spain , Bordeaux, France , Bremen, Germany , Brookhaven, United States , Brooklyn, United States and 61 more locations