Completed PHASE3 INTERVENTIONAL 2-arm NCT00623623

STREAM-Strategic Reperfusion (With Tenecteplase and Antithrombotic Treatment) Early After Myocardial Infarction

STREAM (Strategic Reperfusion Early After Myocardial Infarction). Comparison of the Efficacy and Safety of a Strategy of Early Fibrinolytic Treatment With Tenecteplase and Additional Antiplatelet and Antithrombin Therapy Followed by Catheterisation Within 6-24 Hours or Rescue Coronary Intervention Versus a Strategy of Standard Primary PCI in Patients With Acute Myocardial Infarction Within 3 Hours of Onset of Symptoms

Sponsor: Boehringer Ingelheim

Conditions Myocardial Infarction

Interventions catheterisation clopidogrel enoxaparin primary PCI tenecteplase

Updated 7 times since 2017 Last updated: Jun 6, 2019 Started: Mar 1, 2008 Primary completion: Sep 1, 2012 Completion: Sep 1, 2012

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE3 clinical study on Myocardial Infarction, this trial is completed. The trial is conducted by Boehringer Ingelheim and has accumulated 7 data snapshots since 2008. Cardiovascular trials of this type often inform treatment guidelines for long-term patient management.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Sep 2019 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 2 earlier versions

Jun 2018 — Sep 2019 [monthly]

Completed PHASE3
Jan 2017 — Jun 2018 [monthly]

Completed PHASE3

First recorded

Mar 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Boehringer Ingelheim

Data source: Boehringer Ingelheim

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Alexandroupoli, Greece , Almería, Spain , Ambérieu-en-Bugey, France , Athens, Greece , Aubervilliers, France , Belfast, United Kingdom , Belgrade, Serbia , Berlin, Germany , Besançon, France , Bobigny, France and 100 more locations