Terminated PHASE2 INTERVENTIONAL 3-arm NCT00634322

High Dose Methotrexate With Leucovorin Rescue With or Without Glucarpidase in Osteosarcoma

Randomized, Blinded, Placebo-Controlled Trial of High Dose Methotrexate With Leucovorin Rescue (HDMTX-LV) With or Without Glucarpidase in Osteosarcoma

Sponsor: BTG International Inc.

Conditions Osteosarcoma

Interventions glucarpidase leucovorin

Updated 9 times since 2017 Last updated: Sep 9, 2014 Started: Oct 31, 2008 Primary completion: Mar 31, 2009 Completion: Apr 30, 2009

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Lack of enrollment

Other terminated trials from BTG International Inc.

More terminations from BTG International Inc.

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Listed as NCT00634322, this PHASE2 trial focuses on Osteosarcoma and remains terminated or withdrawn. Sponsored by BTG International Inc., it has been updated 9 times since 2008, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

Change History

9 versions recorded

Sep 2024 — Present [monthly]

Terminated PHASE2
Jul 2024 — Sep 2024 [monthly]

Terminated PHASE2
Jan 2023 — Jul 2024 [monthly]

Terminated PHASE2
Dec 2022 — Jan 2023 [monthly]

Terminated PHASE2
Dec 2021 — Dec 2022 [monthly]

Terminated PHASE2

▶ Show 4 earlier versions

Jan 2021 — Dec 2021 [monthly]

Terminated PHASE2
Jun 2018 — Jan 2021 [monthly]

Terminated PHASE2
Feb 2017 — Jun 2018 [monthly]

Terminated PHASE2
Jan 2017 — Feb 2017 [monthly]

Terminated PHASE2

First recorded

Oct 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

BTG International Inc.
M.D. Anderson Cancer Center

Data source: BTG International Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

No location information available.