deltatrials
Unknown PHASE4 INTERVENTIONAL 4-arm NCT00693849

International Study to Predict Optimised Treatment - in Depression (iSPOT-D)

Sponsor: BRC Operations Pty. Ltd.

Conditions Major Depressive Disorder
Interventions Escitalopram Sertraline Venlafaxine-XR
Updated 8 times since 2017 Last updated: Jul 9, 2018 Started: Sep 30, 2008 Primary completion: Dec 31, 2019 Completion: Dec 31, 2019
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Major Depressive Disorder and is currently ongoing. BRC Operations Pty. Ltd. leads this study, which shows 8 recorded versions since 2008 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotRecruiting~Jun 2018 – ~Aug 2018 · 2 months · monthly snapshotUnknown Status~Aug 2018 – ~Aug 2020 · 24 months · monthly snapshotActive Not Recruiting~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshotUnknown Status~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotUnknown~Sep 2025 – present · 10 months · monthly snapshotUnknown

Change History

8 versions recorded

  1. Sep 2025 — Present [monthly]

    Unknown PHASE4

  2. Sep 2024 — Sep 2025 [monthly]

    Unknown PHASE4

  3. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE4

    Status: Unknown Status → Unknown

  4. Jan 2021 — Jul 2024 [monthly]

    Unknown Status PHASE4

  5. Aug 2020 — Jan 2021 [monthly]

    Unknown Status PHASE4

    Status: Active Not Recruiting → Unknown Status

▶ Show 3 earlier versions

  1. Aug 2018 — Aug 2020 [monthly]

    Active Not Recruiting PHASE4

    Status: Unknown Status → Active Not Recruiting

  2. Jun 2018 — Aug 2018 [monthly]

    Unknown Status PHASE4

    Status: Recruiting → Unknown Status

  3. Jan 2017 — Jun 2018 [monthly]

    Recruiting PHASE4

    First recorded

Sep 2008

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • BRC Operations Pty. Ltd.
Data source: BRC Operations Pty. Ltd.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Adelaide, Australia , Asheville, United States , Auckland, New Zealand , Colton, United States , Columbus, United States , Englewood Cliffs, United States , Johannesburg, South Africa , Melbourne, Australia , Miami, United States , Mission Viejo, United States and 8 more locations