deltatrials
Completed PHASE3 INTERVENTIONAL 4-arm NCT01013649

Gemcitabine Hydrochloride With or Without Erlotinib Hydrochloride Followed by the Same Chemotherapy Regimen With or Without Radiation Therapy and Capecitabine or Fluorouracil in Treating Patients With Pancreatic Cancer That Has Been Removed by Surgery

A Phase II-R and a Phase III Trial Evaluating Both Erlotinib (Ph II-R) and Chemoradiation (Ph III) as Adjuvant Treatment for Patients With Resected Head of Pancreas Adenocarcinoma

Sponsor: NRG Oncology

Updated 77 times since 2017 Last updated: Feb 9, 2026 Started: Apr 5, 2010 Primary completion: Dec 10, 2023 Completion: Sep 4, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Pancreatic Adenocarcinoma and Pancreatic Ductal Adenocarcinoma and is currently completed. NRG Oncology leads this study, which shows 77 recorded versions since 2010 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Mar 2017 · 28 days · monthly snapshot~Mar 2017 – ~May 2017 · 2 months · monthly snapshot~May 2017 – ~Jun 2017 · 31 days · monthly snapshot~Jun 2017 – ~Aug 2017 · 2 months · monthly snapshot~Aug 2017 – ~Sep 2017 · 31 days · monthly snapshot~Sep 2017 – ~Dec 2017 · 3 months · monthly snapshot~Dec 2017 – ~Jan 2018 · 31 days · monthly snapshot~Jan 2018 – ~Mar 2018 · 59 days · monthly snapshot~Mar 2018 – ~Apr 2018 · 31 days · monthly snapshot~Apr 2018 – ~Jun 2018 · 2 months · monthly snapshot~Jun 2018 – ~Jul 2018 · 30 days · monthly snapshot~Jul 2018 – ~Aug 2018 · 31 days · monthly snapshot~Aug 2018 – ~Sep 2018 · 31 days · monthly snapshot~Sep 2018 – ~Oct 2018 · 30 days · monthly snapshot~Oct 2018 – ~Nov 2018 · 31 days · monthly snapshot~Nov 2018 – ~Jan 2019 · 2 months · monthly snapshot~Jan 2019 – ~Feb 2019 · 31 days · monthly snapshot~Feb 2019 – ~Mar 2019 · 28 days · monthly snapshot~Mar 2019 – ~Apr 2019 · 31 days · monthly snapshot~Apr 2019 – ~May 2019 · 30 days · monthly snapshot~May 2019 – ~Jun 2019 · 31 days · monthly snapshot~Jun 2019 – ~Jul 2019 · 30 days · monthly snapshot~Jul 2019 – ~Aug 2019 · 31 days · monthly snapshot~Aug 2019 – ~Sep 2019 · 31 days · monthly snapshot~Sep 2019 – ~Oct 2019 · 30 days · monthly snapshot~Oct 2019 – ~Nov 2019 · 31 days · monthly snapshot~Nov 2019 – ~Dec 2019 · 30 days · monthly snapshot~Dec 2019 – ~Jan 2020 · 31 days · monthly snapshot~Jan 2020 – ~Feb 2020 · 31 days · monthly snapshot~Feb 2020 – ~Mar 2020 · 29 days · monthly snapshot~Mar 2020 – ~Apr 2020 · 31 days · monthly snapshot~Apr 2020 – ~May 2020 · 30 days · monthly snapshot~May 2020 – ~Jun 2020 · 31 days · monthly snapshot~Jun 2020 – ~Jul 2020 · 30 days · monthly snapshot~Jul 2020 – ~Sep 2020 · 2 months · monthly snapshot~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Apr 2021 · 59 days · monthly snapshot~Apr 2021 – ~Jun 2021 · 2 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Mar 2022 · 5 months · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jul 2022 · 2 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Apr 2023 · 4 months · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Jan 2024 · 3 months · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~Jun 2024 · 2 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Jan 2025 · 2 months · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~Apr 2025 · 31 days · monthly snapshot~Apr 2025 – ~Jun 2025 · 2 months · monthly snapshot~Jun 2025 – ~Aug 2025 · 2 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Feb 2026 · 3 months · monthly snapshot~Feb 2026 – present · 3 months · monthly snapshot

Change History

77 versions recorded
  1. Feb 2026 — Present [monthly]

    Completed PHASE3

  2. Nov 2025 — Feb 2026 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  3. Oct 2025 — Nov 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Sep 2025 — Oct 2025 [monthly]

    Active Not Recruiting PHASE3

  5. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

Show 72 earlier versions
  1. Jun 2025 — Aug 2025 [monthly]

    Active Not Recruiting PHASE3

  2. Apr 2025 — Jun 2025 [monthly]

    Active Not Recruiting PHASE3

  3. Mar 2025 — Apr 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Feb 2025 — Mar 2025 [monthly]

    Active Not Recruiting PHASE3

  5. Jan 2025 — Feb 2025 [monthly]

    Active Not Recruiting PHASE3

  6. Nov 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE3

  7. Sep 2024 — Nov 2024 [monthly]

    Active Not Recruiting PHASE3

  8. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

  9. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

  10. Apr 2024 — Jun 2024 [monthly]

    Active Not Recruiting PHASE3

    Phase: PHASE2_PHASE3PHASE3

  11. Mar 2024 — Apr 2024 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  12. Feb 2024 — Mar 2024 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  13. Jan 2024 — Feb 2024 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  14. Oct 2023 — Jan 2024 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  15. Sep 2023 — Oct 2023 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  16. Aug 2023 — Sep 2023 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  17. Jul 2023 — Aug 2023 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  18. Jun 2023 — Jul 2023 [monthly]

    Active Not Recruiting PHASE2_PHASE3

    Phase: PHASE3PHASE2_PHASE3

  19. May 2023 — Jun 2023 [monthly]

    Active Not Recruiting PHASE3

  20. Apr 2023 — May 2023 [monthly]

    Active Not Recruiting PHASE3

  21. Dec 2022 — Apr 2023 [monthly]

    Active Not Recruiting PHASE3

  22. Sep 2022 — Dec 2022 [monthly]

    Active Not Recruiting PHASE3

  23. Jul 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE3

  24. May 2022 — Jul 2022 [monthly]

    Active Not Recruiting PHASE3

  25. Apr 2022 — May 2022 [monthly]

    Active Not Recruiting PHASE3

  26. Mar 2022 — Apr 2022 [monthly]

    Active Not Recruiting PHASE3

  27. Oct 2021 — Mar 2022 [monthly]

    Active Not Recruiting PHASE3

  28. Sep 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE3

  29. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE3

  30. Apr 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE3

  31. Feb 2021 — Apr 2021 [monthly]

    Active Not Recruiting PHASE3

  32. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE3

  33. Dec 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  34. Nov 2020 — Dec 2020 [monthly]

    Active Not Recruiting PHASE3

  35. Oct 2020 — Nov 2020 [monthly]

    Active Not Recruiting PHASE3

  36. Sep 2020 — Oct 2020 [monthly]

    Active Not Recruiting PHASE3

  37. Jul 2020 — Sep 2020 [monthly]

    Active Not Recruiting PHASE3

  38. Jun 2020 — Jul 2020 [monthly]

    Active Not Recruiting PHASE3

  39. May 2020 — Jun 2020 [monthly]

    Active Not Recruiting PHASE3

  40. Apr 2020 — May 2020 [monthly]

    Active Not Recruiting PHASE3

  41. Mar 2020 — Apr 2020 [monthly]

    Active Not Recruiting PHASE3

  42. Feb 2020 — Mar 2020 [monthly]

    Active Not Recruiting PHASE3

  43. Jan 2020 — Feb 2020 [monthly]

    Active Not Recruiting PHASE3

  44. Dec 2019 — Jan 2020 [monthly]

    Active Not Recruiting PHASE3

  45. Nov 2019 — Dec 2019 [monthly]

    Active Not Recruiting PHASE3

  46. Oct 2019 — Nov 2019 [monthly]

    Active Not Recruiting PHASE3

  47. Sep 2019 — Oct 2019 [monthly]

    Active Not Recruiting PHASE3

  48. Aug 2019 — Sep 2019 [monthly]

    Active Not Recruiting PHASE3

  49. Jul 2019 — Aug 2019 [monthly]

    Active Not Recruiting PHASE3

  50. Jun 2019 — Jul 2019 [monthly]

    Active Not Recruiting PHASE3

  51. May 2019 — Jun 2019 [monthly]

    Active Not Recruiting PHASE3

  52. Apr 2019 — May 2019 [monthly]

    Active Not Recruiting PHASE3

  53. Mar 2019 — Apr 2019 [monthly]

    Active Not Recruiting PHASE3

  54. Feb 2019 — Mar 2019 [monthly]

    Active Not Recruiting PHASE3

  55. Jan 2019 — Feb 2019 [monthly]

    Active Not Recruiting PHASE3

  56. Nov 2018 — Jan 2019 [monthly]

    Active Not Recruiting PHASE3

  57. Oct 2018 — Nov 2018 [monthly]

    Active Not Recruiting PHASE3

  58. Sep 2018 — Oct 2018 [monthly]

    Active Not Recruiting PHASE3

  59. Aug 2018 — Sep 2018 [monthly]

    Active Not Recruiting PHASE3

  60. Jul 2018 — Aug 2018 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  61. Jun 2018 — Jul 2018 [monthly]

    Recruiting PHASE3

  62. Apr 2018 — Jun 2018 [monthly]

    Recruiting PHASE3

  63. Mar 2018 — Apr 2018 [monthly]

    Recruiting PHASE3

  64. Jan 2018 — Mar 2018 [monthly]

    Recruiting PHASE3

  65. Dec 2017 — Jan 2018 [monthly]

    Recruiting PHASE3

  66. Sep 2017 — Dec 2017 [monthly]

    Recruiting PHASE3

  67. Aug 2017 — Sep 2017 [monthly]

    Recruiting PHASE3

  68. Jun 2017 — Aug 2017 [monthly]

    Recruiting PHASE3

  69. May 2017 — Jun 2017 [monthly]

    Recruiting PHASE3

  70. Mar 2017 — May 2017 [monthly]

    Recruiting PHASE3

  71. Feb 2017 — Mar 2017 [monthly]

    Recruiting PHASE3

  72. Jan 2017 — Feb 2017 [monthly]

    Recruiting PHASE3

    First recorded

Apr 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • NRG Oncology
  • National Cancer Institute (NCI)
Data source: National Cancer Institute (NCI)

For direct contact, visit the study record on ClinicalTrials.gov .