Completed PHASE3 INTERVENTIONAL 2-arm NCT01042977

Efficacy and Safety in Patients With Type 2 Diabetes Mellitus and Cardiovascular Disease

A 24-week, Multicentre, Randomised, Double-blind,Age-stratified, Placebo Controlled Phase III Study With an 80-week Extension Period to Evaluate the Efficacy and Safety of Dapagliflozin 10 mg Once Daily in Patients With T2DM and Cardiovascular Disease, Who Exhibit Inadequate Glycaemic Control on Usual Care

Sponsor: AstraZeneca

Conditions Cardiovascular Disease Inadequate Glycaemic Control Type 2 Diabetes Mellitus

Interventions Dapagliflozin Placebo

Updated 8 times since 2017 Last updated: Dec 18, 2013 Started: Mar 31, 2010 Primary completion: May 31, 2011 Completion: Dec 31, 2012

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Cardiovascular Disease and Inadequate Glycaemic Control and is currently completed. AstraZeneca leads this study, which shows 8 recorded versions since 2010 — indicating limited longitudinal coverage. Heart and vascular conditions benefit from the kind of long-term tracking this trial provides.

Status Flow

Change History

8 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Dec 2021 — Jul 2024 [monthly]

Completed PHASE3
Jan 2021 — Dec 2021 [monthly]

Completed PHASE3

▶ Show 3 earlier versions

Jun 2018 — Jan 2021 [monthly]

Completed PHASE3
Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Mar 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

AstraZeneca
Bristol-Myers Squibb

Data source: AstraZeneca

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Adelaide, Australia , Ajka, Hungary , Alexandria, United States , Altoona, United States , Anaheim, United States , Asheboro, United States , Austin, United States , Aventura, United States , Avon, United States , Balatonfüred, Hungary and 124 more locations