Comparison of Brivanib and Best Supportive Care (BSC) With Placebo and BSC for Treatment of Liver Cancer in Asian Patients Who Have Failed Sorafenib Treatment (BRISK-APS)
A Randomized, Double-blind, Multi-center Phase III Study of Brivanib Plus Best Supportive Care (BSC) Versus Placebo Plus BSC in Asian Subjects With Advanced Hepatocellular Carcinoma (HCC) Who Have Failed or Are Intolerant to Sorafenib
Sponsor: Bristol-Myers Squibb
Terminated
This trial was terminated. No reason was provided.
Other terminated trials from Bristol-Myers Squibb
Other Carcinoma, Hepatocellular trials with similar outcome
A PHASE3 clinical study on Carcinoma, Hepatocellular, this trial is terminated or withdrawn. The trial is conducted by Bristol-Myers Squibb and has accumulated 8 data snapshots since 2010. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.
Status Flow
Change History
8 versions recorded-
Sep 2025 — Present [monthly]
Terminated PHASE3
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Sep 2024 — Sep 2025 [monthly]
Terminated PHASE3
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Jul 2024 — Sep 2024 [monthly]
Terminated PHASE3
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Apr 2022 — Jul 2024 [monthly]
Terminated PHASE3
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Jan 2021 — Apr 2022 [monthly]
Terminated PHASE3
▶ Show 3 earlier versions
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Jun 2018 — Jan 2021 [monthly]
Terminated PHASE3
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Feb 2017 — Jun 2018 [monthly]
Terminated PHASE3
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Jan 2017 — Feb 2017 [monthly]
Terminated PHASE3
First recorded
May 2010
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Bristol-Myers Squibb
For direct contact, visit the study record on ClinicalTrials.gov .
Study Locations
Beijing, China , Changchun, China , Chengdu, China , Chongqing, China , Fuzhou, China , Guangzhou, China , Guanzhou, China , Gyeonggi-do, South Korea , Hangzhou, China , Hankou, China and 14 more locations