deltatrials
Unknown PHASE3 INTERVENTIONAL 2-arm NCT01112072

Corneal Collagen Crosslinking and Intacs for Keratoconus and Ectasia (CXL)

Randomized Study of Safety and Effectiveness of Corneal Collagen Crosslinking and Intacs for Treatment of Keratoconus and Corneal Ectasia

Sponsor: Cornea and Laser Eye Institute

Interventions Riboflavin
Updated 13 times since 2017 Last updated: Feb 6, 2023 Started: Apr 30, 2010 Primary completion: Dec 31, 2024 Completion: Dec 31, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01112072, this PHASE3 trial focuses on Corneal Ectasia and Keratoconus and remains ongoing. Sponsored by Cornea and Laser Eye Institute, it has been updated 13 times since 2010, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Jun 2018 · 16 months · monthly snapshot~Jun 2018 – ~Feb 2019 · 8 months · monthly snapshot~Feb 2019 – ~Feb 2020 · 12 months · monthly snapshot~Feb 2020 – ~Jan 2021 · 11 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Jun 2021 · 4 months · monthly snapshot~Jun 2021 – ~Apr 2022 · 10 months · monthly snapshot~Apr 2022 – ~Mar 2023 · 11 months · monthly snapshot~Mar 2023 – ~Jul 2024 · 16 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2026 · 17 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

13 versions recorded
  1. Feb 2026 — Present [monthly]

    Unknown PHASE3

    Status: Active Not RecruitingUnknown

  2. Sep 2024 — Feb 2026 [monthly]

    Active Not Recruiting PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

  4. Mar 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

  5. Apr 2022 — Mar 2023 [monthly]

    Active Not Recruiting PHASE3

Show 8 earlier versions
  1. Jun 2021 — Apr 2022 [monthly]

    Active Not Recruiting PHASE3

  2. Feb 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE3

  3. Jan 2021 — Feb 2021 [monthly]

    Active Not Recruiting PHASE3

  4. Feb 2020 — Jan 2021 [monthly]

    Active Not Recruiting PHASE3

  5. Feb 2019 — Feb 2020 [monthly]

    Active Not Recruiting PHASE3

  6. Jun 2018 — Feb 2019 [monthly]

    Active Not Recruiting PHASE3

  7. Feb 2017 — Jun 2018 [monthly]

    Active Not Recruiting PHASE3

  8. Jan 2017 — Feb 2017 [monthly]

    Active Not Recruiting PHASE3

    First recorded

Apr 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cornea and Laser Eye Institute
Data source: Cornea and Laser Eye Institute

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations