Reduced Radiotherapy With Pac/Cis vs Standard Radiotherapy With 5-FU/Cis in Locally Advanced Head and Neck Cancer (Paccis-RCT)
Randomised Phase-III-trial of Simultaneous Radiochemotherapy (RCT) of Locally Advanced Head and Neck Cancer in the Stages III and IV A-B: Comparing Dose Reduced Radiotherapy (63,6 Gy) With Paclitaxel/Cisplatin to Standard Radiotherapy (70,2 Gy) With 5-Fluorouracil/Cisplatin
Sponsor: Deutsche Krebshilfe e.V., Bonn (Germany)
Terminated
After an Interims analysis the Data Safety Monitoring board recommended this because no significant difference between the two arms was seen and was not expected with an reasonable recruitment of patients.~No interruptions of the trial were made.
Other terminated trials from Deutsche Krebshilfe e.V., Bonn (Germany)
See all terminations from Deutsche Krebshilfe e.V., Bonn (Germany)
A PHASE3 clinical study on Head and Neck Cancer, this trial is terminated or withdrawn. The trial is conducted by Deutsche Krebshilfe e.V., Bonn (Germany) and has accumulated 8 data snapshots since 2010. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.
Status Flow
Change History
8 versions recorded-
Sep 2024 — Present [monthly]
Terminated PHASE3
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Jul 2024 — Sep 2024 [monthly]
Terminated PHASE3
-
Dec 2021 — Jul 2024 [monthly]
Terminated PHASE3
-
Jun 2021 — Dec 2021 [monthly]
Terminated PHASE3
Status: Unknown Status → Terminated
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Jan 2021 — Jun 2021 [monthly]
Unknown Status PHASE3
▶ Show 3 earlier versions
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Sep 2019 — Jan 2021 [monthly]
Unknown Status PHASE3
Status: Active Not Recruiting → Unknown Status
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Jun 2018 — Sep 2019 [monthly]
Active Not Recruiting PHASE3
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Jan 2017 — Jun 2018 [monthly]
Active Not Recruiting PHASE3
First recorded
Jun 2010
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Deutsche Krebshilfe e.V., Bonn (Germany)
- University of Erlangen-Nürnberg Medical School
For direct contact, visit the study record on ClinicalTrials.gov .
Study Locations
Coburg, Germany , Düsseldorf, Germany , Erlangen, Germany , Frankfurt/M., Germany , Göppingen, Germany , Homburg/Saar, Germany , Lübeck, Germany , Mönchengladbach, Germany , München, Germany , Paderborn, Germany and 3 more locations