deltatrials
Completed PHASE2 INTERVENTIONAL 3-arm NCT01181401

InductionChemo-Radio-Antibody-Treatment (ICRAT)

Randomized Phase II Study of Two Different Regimens of TPF Induction Chemotherapy Regimen Followed by Radiation Therapy Plus Cetuximab (TPF-CET-HART) vs. HART and Cis-platinum, 5-FU (PF-HART) in Patients With Locally Advanced Unresectable Squamous Cell Carcinomas of the Head and Neck

Sponsor: Charite University, Berlin, Germany

Conditions Squamous Cell Carcinoma of the Head Squamous Cell Carcinoma of the Neck
Interventions Standard Radiochemotherapy (HART) TPF experimental TPF induction chemotherapy
Updated 7 times since 2017 Last updated: Jan 29, 2019 Started: Aug 31, 2010 Primary completion: Apr 30, 2015 Completion: Aug 31, 2015
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Squamous Cell Carcinoma of the Head and Squamous Cell Carcinoma of the Neck, this trial is completed. The trial is conducted by Charite University, Berlin, Germany and has accumulated 7 data snapshots since 2010. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Jan 2017 – ~Jun 2018 · 17 months · monthly snapshotUnknown Status~Jun 2018 – ~Feb 2019 · 8 months · monthly snapshotUnknown Status~Feb 2019 – ~Jan 2021 · 23 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

7 versions recorded

  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE2

  5. Feb 2019 — Jan 2021 [monthly]

    Completed PHASE2

    Status: Unknown Status → Completed

▶ Show 2 earlier versions

  1. Jun 2018 — Feb 2019 [monthly]

    Unknown Status PHASE2

  2. Jan 2017 — Jun 2018 [monthly]

    Unknown Status PHASE2

    First recorded

Aug 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Charite University, Berlin, Germany
Data source: Charite University, Berlin, Germany

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations