deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT01200992

Efficacy and Safety Evaluation of EN3348 (Mycobacterial Cell Wall-DNA Complex [MCC]) as Compared With Mitomycin C in the Intravesical Treatment of Subjects With BCG Recurrent/Refractory Non-muscle Invasive Bladder Cancer (EMBARC-RF)

A Phase 3, Randomized, Active-Controlled, Open-Label, Multicenter Study to Evaluate the Efficacy and Safety of EN3348 (MCC) as Compared With Mitomycin C in the Intravesical Treatment of Subjects With BCG Recurrent or Refractory Non-Muscle Invasive Bladder Cancer

Sponsor: Bioniche Life Sciences Inc.

Updated 8 times since 2017 Last updated: Aug 23, 2017 Started: Nov 30, 2010 Primary completion: Apr 30, 2013 Completion: Dec 31, 2013
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Lack of Recruitment

Listed as NCT01200992, this PHASE3 trial focuses on Bladder Neoplasm and Carcinoma in Situ and remains terminated or withdrawn. Sponsored by Bioniche Life Sciences Inc., it has been updated 8 times since 2010, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotTerminated~Feb 2017 – ~Sep 2017 · 7 months · monthly snapshotTerminated~Sep 2017 – ~Jun 2018 · 9 months · monthly snapshotTerminated~Jun 2018 – ~Jan 2021 · 31 months · monthly snapshotTerminated~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 12 months · monthly snapshotTerminated

Change History

8 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  4. Jan 2021 — Jul 2024 [monthly]

    Terminated PHASE3

  5. Jun 2018 — Jan 2021 [monthly]

    Terminated PHASE3

Show 3 earlier versions
  1. Sep 2017 — Jun 2018 [monthly]

    Terminated PHASE3

  2. Feb 2017 — Sep 2017 [monthly]

    Terminated PHASE3

  3. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE3

    First recorded

Nov 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bioniche Life Sciences Inc.
Data source: Bioniche Life Sciences Inc.

For direct contact, visit the study record on ClinicalTrials.gov .