Completed PHASE3 INTERVENTIONAL 2-arm NCT00440310

Phase 3 Trial of Litx™ Plus Chemotherapy vs. Chemotherapy Only Treating Colorectal Cancer Patients With Recurrent Liver Metastases

A Multicenter Multinational Phase 3 Randomized Study to Evaluate the Safety and Efficacy of Treating Colorectal Cancer Patients With Recurrent Liver Metastases Using the Litx™ System Plus Chemotherapy as Compared to Chemotherapy Only

Sponsor: Light Sciences Oncology

Conditions Colorectal Neoplasms Liver Metastases Neoplasm Metastasis Neoplasm Recurrence, Local

Interventions FOLFIRI regimen FOLFOX4 regimen Interstitial light emitting diodes Percutaneous placement of device in liver metastases Talaporfin sodium

Updated 7 times since 2017 Last updated: Jul 28, 2015 Started: Feb 28, 2007 Primary completion: May 31, 2011 Completion: Oct 31, 2011

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE3 trial investigates Colorectal Neoplasms and Liver Metastases and is currently completed. Light Sciences Oncology leads this study, which shows 7 recorded versions since 2007 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Completed PHASE3
Sep 2024 — Sep 2025 [monthly]

Completed PHASE3
Jul 2024 — Sep 2024 [monthly]

Completed PHASE3
Jan 2021 — Jul 2024 [monthly]

Completed PHASE3
Jun 2018 — Jan 2021 [monthly]

Completed PHASE3

▶ Show 2 earlier versions

Feb 2017 — Jun 2018 [monthly]

Completed PHASE3
Jan 2017 — Feb 2017 [monthly]

Completed PHASE3

First recorded

Feb 2007

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Light Sciences Oncology

Data source: Light Sciences Oncology

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Aalen, Germany , Ancona, Italy , Aurangabad, India , Bangalore, India , Barmaul, Russia , Belgrade, Serbia , Bhopal, India , Borna, Germany , Bucharest, Romania , Cherkassy, Ukraine and 39 more locations