deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT01227824

A Trial Comparing GSK1349572 50mg Once Daily to Raltegravir 400mg Twice Daily (SPRING-2)

A Randomized, Double Blind Study of the Safety and Efficacy of GSK1349572 50mg Once Daily to Raltegravir 400mg Twice Daily Both Administered With Fixed-dose Dual Nucleoside Reverse Transcriptase Inhibitor Therapy Over 96 Weeks in HIV-1 Infected Antiretroviral Therapy Naive Adult Subjects

Sponsor: GlaxoSmithKline

Updated 9 times since 2017 Last updated: Oct 4, 2018 Started: Oct 19, 2010 Primary completion: Feb 6, 2012 Completion: Dec 27, 2016
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT01227824, this PHASE3 trial focuses on Infection, Human Immunodeficiency Virus I and remains completed. Sponsored by GlaxoSmithKline, it has been updated 9 times since 2010, reflecting limited change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshotUnknown Status~Feb 2017 – ~Feb 2018 · 12 months · monthly snapshotUnknown Status~Feb 2018 – ~Jun 2018 · 4 months · monthly snapshotCompleted~Jun 2018 – ~Nov 2018 · 5 months · monthly snapshotCompleted~Nov 2018 – ~Jan 2021 · 26 months · monthly snapshotCompleted~Jan 2021 – ~Jul 2024 · 42 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  4. Jan 2021 — Jul 2024 [monthly]

    Completed PHASE3

  5. Nov 2018 — Jan 2021 [monthly]

    Completed PHASE3

Show 4 earlier versions
  1. Jun 2018 — Nov 2018 [monthly]

    Completed PHASE3

  2. Feb 2018 — Jun 2018 [monthly]

    Completed PHASE3

    Status: Unknown StatusCompleted

  3. Feb 2017 — Feb 2018 [monthly]

    Unknown Status PHASE3

  4. Jan 2017 — Feb 2017 [monthly]

    Unknown Status PHASE3

    First recorded

Oct 2010

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • GlaxoSmithKline
  • Shionogi
  • ViiV Healthcare
Data source: ViiV Healthcare

For direct contact, visit the study record on ClinicalTrials.gov .