deltatrials
Terminated PHASE3 INTERVENTIONAL 3-arm NCT01316939

GSK1605786A in the Maintenance of Remission in Subjects With Crohn's Disease (SHIELD-2)

A 52 Week Randomised, Double-blind, Placebo-controlled Study to Investigate the Efficacy and Safety of GSK1605786A in the Maintenance of Remission in Subjects With Crohn's Disease

Sponsor: GlaxoSmithKline

Updated 13 times since 2017 Last updated: Aug 7, 2017 Started: May 9, 2011 Primary completion: Oct 23, 2013 Completion: Oct 23, 2013
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

This study was terminated due to the lack of efficacy of GSK1605786A in Crohn's disease based on the results of Study CCX114151.

Listed as NCT01316939, this PHASE3 trial focuses on Crohn's Disease and remains terminated or withdrawn. Sponsored by GlaxoSmithKline, it has been updated 13 times since 2011, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2017 – ~Feb 2017 · 31 days · monthly snapshot~Feb 2017 – ~Aug 2017 · 6 months · monthly snapshot~Aug 2017 – ~Oct 2017 · 2 months · monthly snapshot~Oct 2017 – ~May 2018 · 7 months · monthly snapshot~May 2018 – ~Jun 2018 · 31 days · monthly snapshot~Jun 2018 – ~Sep 2020 · 27 months · monthly snapshot~Sep 2020 – ~Nov 2020 · 2 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Dec 2021 · 11 months · monthly snapshot~Dec 2021 – ~Jul 2024 · 31 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – present · 10 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  4. Dec 2021 — Jul 2024 [monthly]

    Terminated PHASE3

  5. Jan 2021 — Dec 2021 [monthly]

    Terminated PHASE3

Show 8 earlier versions
  1. Nov 2020 — Jan 2021 [monthly]

    Terminated PHASE3

  2. Sep 2020 — Nov 2020 [monthly]

    Terminated PHASE3

  3. Jun 2018 — Sep 2020 [monthly]

    Terminated PHASE3

  4. May 2018 — Jun 2018 [monthly]

    Terminated PHASE3

  5. Oct 2017 — May 2018 [monthly]

    Terminated PHASE3

  6. Aug 2017 — Oct 2017 [monthly]

    Terminated PHASE3

  7. Feb 2017 — Aug 2017 [monthly]

    Terminated PHASE3

  8. Jan 2017 — Feb 2017 [monthly]

    Terminated PHASE3

    First recorded

May 2011

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • GlaxoSmithKline
Data source: GlaxoSmithKline

For direct contact, visit the study record on ClinicalTrials.gov .